Results 61 to 70 of about 5,187,702 (267)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Molecular Hydrogen Line Identifications in Solar Flares Observed by IRIS: Lower Atmospheric Structure from Radiometric Analysis

The Astrophysical Journal
A rich spectrum of molecular hydrogen (H _2 ) emission lines is seen in sensitive observations from the far-ultraviolet (FUV) channels of the Interface Region Imaging Spectrograph (IRIS) during flare activity in solar active region NOAA Active Region ...
Sarah A. Jaeggli, Adrian N. Daw
doaj   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Hot Methane Spectra for Astrophysical Applications [PDF]

, 2012
In this thesis line lists for methane (CH4) are presented. These line lists were obtained at high temperatures (300-1400 oC at 100 oC intervals) by recording infrared emission spectra with a tube furnace to heat to the required temperatures and a Fourier
Beale, Christopher
core   +4 more sources

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Line List for the A2Π−X2Σ+ and the B2Σ+−X2Σ+ Band Systems of CaF

The Astrophysical Journal
The spectral analysis of molecule-rich asymptotic giant branch (AGB) stars is challenging. Although other calcium and fluorine bearing molecules are observed in the microwave and in the visible spectrum of AGB stars, CaF has never been detected, despite ...
Léo Lavy, Peter F Bernath, Adam Pastorek   +2 more
doaj   +1 more source

Comparison Between Hitran2012 Data And A New Experimental Line List Recently Published For Water Vapor In The Spectral Region 6450 To 9400 Cm⁻¹

, 2014
Recently an experimental list of water absorption lines between 6450 and 9400 cm−1 has been published by Régalia et al.1 This paper includes detailed comparison with HITRAN20082 and GEISA20093 databases. Before the end of the redaction of this article1, the new version of the HITRAN database4 was published.
Mikhailenko, S., Régalia, L.
openaire   +2 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Visible Opacities of S-type Stars: The d 3Φ–a 3Δ Band System of ZrO

The Astrophysical Journal
ZrO is a well-studied metal monoxide because of its astrophysical importance in characterizing S stars. The bands of the d ^3 Φ–a ^3 Δ system ( γ system) with ${v}^{{\prime} }\leqslant 4$ and v ″ ≤ 5 are rotationally analyzed using the PGOPHER program to
Peter F. Bernath, Manish Bhusal, Jacques Liévin   +2 more
doaj   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source