Results 71 to 80 of about 479,061 (253)
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Accurate Chebyshev collocation solutions for the biharmonic eigenproblem on a rectangle
We are concerned with accurate Chebyshev collocation (ChC) solutions to fourth order eigenvalue problems. We consider the 1D case as well as the 2D case.
Imre Boros
doaj +2 more sources
Spectral Methods for Response Enhancement of Microwave Resonant Sensors in Continuous Non-Invasive Blood Glucose Monitoring. [PDF]
Buonanno G +3 more
europepmc +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Thermal analysis of extended surfaces using deep neural networks
The complexity of thermal analysis in practical systems has emerged as a subject of interest in various fields of science and engineering. Extended surfaces, commonly called fins, are crucial cooling and heating mechanisms in many applications, such as ...
Oloniiju Shina Daniel +2 more
doaj +1 more source
Novel derivative operational matrix in Caputo sense with applications
The main objective of this study is to present a computationally efficient numerical method for solving fractional-order differential equations with initial conditions.
Danish Zaidi +3 more
doaj +1 more source
Starting from theophylline (1,3-dimethylxanthine) new thiazolidin-4-one derivatives 7a1–7, 7b1–7 have been synthesized as potential antidiabetic drugs.
Lenuta Profire +4 more
doaj +1 more source
Compressive Spectral Renormalization Method
In this paper a novel numerical scheme for finding the sparse self-localized states of a nonlinear system of equations with missing spectral data is introduced. As in the Petviashivili's and the spectral renormalization method, the governing equation is transformed into Fourier domain, but the iterations are performed for far fewer number of spectral ...
openaire +4 more sources
Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring +3 more
wiley +1 more source

