Results 91 to 100 of about 1,565,423 (283)

Spectral methods for inviscid, compressible flows [PDF]

open access: yes
Report developments in the application of spectral methods to two dimensional compressible flows are reviewed. A brief introduction to spectral methods -- their history and especially their implementation -- is provided. The stress is on those techniques
Hussaini, M. Y.   +2 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Efficient Spectral Galerkin and Collocation Approaches Using Telephone Polynomials for Solving Some Models of Differential Equations with Convergence Analysis

open access: yesMathematics
This study presents Galerkin and collocation algorithms based on Telephone polynomials (TelPs) for effectively solving high-order linear and non-linear ordinary differential equations (ODEs) and ODE systems, including those with homogeneous and ...
Ramy Mahmoud Hafez   +4 more
doaj   +1 more source

Synthesis and Biological Evaluation of New 1,3-Thiazolidine-4-one Derivatives of 2-(4-Isobutylphenyl)propionic Acid

open access: yesMolecules, 2014
New thiazolidine-4-one derivatives of 2-(4-isobutylphenyl)propionic acid (ibuprofen) have been synthesized as potential anti-inflammatory drugs. The structure of the new compounds was proved using spectral methods (FR-IR, 1H-NMR, 13C-NMR, MS).
Ioana Mirela Vasincu   +5 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Seismic Response Analysis of a Six-Story Building in Sofia Using Accelerograms from the 2012 Mw5.6 Pernik Earthquake

open access: yesApplied Sciences
On 22 May 2012, a magnitude Mw 5.6 earthquake struck the Pernik region of western Bulgaria, causing structural damage in nearby cities, including Sofia. This study assesses the seismic response of a six-story reinforced concrete building in central Sofia,
Lyubka Pashova   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

High-Order Spectral Scheme with Structure Maintenance and Fast Memory Algorithm for Nonlocal Nonlinear Diffusion Equations

open access: yesAppliedMath
We develop a fast numerical method for solving nonlinear diffusion equations with memory phenomena, a class of problems arising within viscoelastic materials, anomalous transport, and hereditary systems.
Kadrzhan Shiyapov   +3 more
doaj   +1 more source

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