Results 91 to 100 of about 137,938 (302)

Modulation of Spectral Representation and Connectivity Patterns in Response to Visual Narrative in the Human Brain. [PDF]

Front Hum Neurosci, 2022
Sabra Z, Alawieh A, Bonilha L, Naselaris T, AuYong N.   +4 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Tdnn-Based Engine In-Cylinder Pressure Estimation from Shaft Velocity Spectral Representation. [PDF]

Sensors (Basel), 2021
Valencia-Duque AF, Cárdenas-Peña DA, Álvarez-Meza AM, Orozco-Gutiérrez ÁA, Quintero-Riaza HF.   +4 more
europepmc   +1 more source

Vector-exponential time-series modeling for polynomial J-spectral factorization

, 2005
An iterative algorithm to perform the J-spectral factorization of a para-Hermitian matrix is presented. The algorithm proceeds by computing a special kernel representation of an interpolant for a sequence of points and associated directions determined ...
Pendharkar, Ishan, Pillai, Harish K., Rapisarda, Paolo   +2 more
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Existence of spectral well-behaved ∗-representations

Journal of Mathematical Analysis and Applications, 2006
Given an unbounded \(m^{*}\)-seminorm \(p\) of a \(*\)-algebra, a \(p\)-spectral \(*\)-representation is studied in connection with well-behaved \(*\)-representations. The existence of well-behaved \(p\)-spectral \(*\)-representations on \(*\)-algebras is characterized through certain properties of Ptak functions on the domain of \(p\).
Bhatt, S.J., Fragoulopoulou, M., Inoue, A.   +2 more
openaire   +2 more sources

Cortical Mechanisms for the Segregation and Representation of Acoustic Textures

, 2010
Auditory object analysis requires two fundamental perceptual processes: the definition of the boundaries between objects, and the abstraction and maintenance of an object's characteristic features. Although it is intuitive to assume that the detection of
Stewart, Lauren, Griffiths, Timothy D., Overath, T., von Kriegstein, K., von Kriegstein, Katharina, Cusack, Rhodri, TD, Griffiths, Rees, Adrian, von Kriegstein, K, Rees, A, Stewart, L., Cusack, R., Griffiths, T., Overath, T, Kumar, S, Stewart, L; id_orcid, Rees, A., Kumar, S., Overath, Tobias, Kumar, Sukhbinder, Cusack, R   +20 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source