Results 81 to 90 of about 6,265,192 (292)

Study on Rapid Recognition of Marine Microplastics Based on Raman Spectroscopy

open access: yes, 2021
Due to a large amount of use and discharge of plastics, these plastics are broken into microplastics by the environmental effect and gather in the ocean in large quantities, leading to the accumulation of a large number of microplastics in the ocean ...
Wang Qing   +3 more
core   +1 more source

Mathematical Stability Analysis of the Full SREBP-2 Pathway Model: Insights into Cholesterol Homeostasis

open access: yesAxioms
We present a mathematical analysis of the sterol regulatory element-binding protein 2 (SREBP-2) pathway, a key regulator of intracellular cholesterol homeostasis.
Mostafa Bachar
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

On the continuity of the map square root of nonnegative isomorphisms in Hilbert spaces

open access: yesRevista Integración, 2015
Let H be a real (or complex) Hilbert space. Every nonnegative operator L ∈ L(H) admits a unique nonnegative square root R ∈ L(H), i.e., a nonnegative operator R ∈ L(H) such that R2 = L.
Jeovanny de Jesus Muentes Acevedo
doaj  

The Self-Adjoint Fractional Heun Operator and Its Spectral Properties

open access: yesMathematics
This paper introduces a rigorously defined fractional Heun operator constructed through a symmetric composition of left and right Riemann–Liouville fractional derivatives.
Muath Awadalla
doaj   +1 more source

Persistent spectral theory-guided protein engineering. [PDF]

open access: yesNat Comput Sci, 2023
Qiu Y, Wei GW, Wei GW.
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Spectral properties of the internal wave operator in nonclassical problems

open access: yesСовременная математика: Фундаментальные направления
This study examines the small oscillations of an ideal stratified fluid within bounded domains. In classical formulations of these problems, the lateral boundaries of the container are typically assumed to align with the gravity vector g and the ...
Y. Zhang, A. N. Temnov
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

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