Results 101 to 110 of about 2,120,250 (297)

A Spectral Variability and Class-Constrained Diffusion Model for Unsupervised Hyperspectral Unmixing

open access: yesRemote Sensing
Hyperspectral remote sensing is increasingly utilized due to its high spectral resolution and broad observational capabilities, and hyperspectral unmixing aims to decompose mixed pixels into their constituent endmembers with corresponding classes.
Mingwei Wang   +4 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

X-ray Flux and Spectral Variability of Blazar H 2356-309

open access: yesGalaxies, 2020
We present the results of timing and spectral analysis of the blazar H 2356-309 using XMM-Newton observations. This blazar is observed during 13 June 2005–24 December 2013 in total nine observations.
Kiran A. Wani, Haritma Gaur
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Development of a new spectral library classifier for airborne hyperspectral images on heterogeneous environments [PDF]

open access: yes, 2011
The classification of hyperspectral images on heterogeneous environments without prior knowledge about the study area is a challenging task. Finding potential pure spectral signatures or endmembers (EM) of the various surface materials within an image is
Mende, Andre   +4 more
core  

Estimating the irradiance spectrum from measurements in a limited number of spectral bands

open access: yes, 2006
Accurate measurement and characterisation of fluctuations in the irradiance environment is important for many areas of optical remote sensing. This paper describes a method of estimating spectral irradiance over the region 400 – 1000 nm from the radiance
Milton, E.J., Rollin, E.M.
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

An extended spectral angle map for hyperspectral and multispectral imaging

open access: yes
We present an extension to the widely used spectral angle metric, calculating an azimuthal angle around a reference vector. We demonstrate that it provides additional information, thus improving the classification ability of the spectral ...
Rutt, Harvey   +2 more
core   +1 more source

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