Results 121 to 130 of about 2,215,341 (299)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

LiDAR-GUIDED REDUCTION OF SPECTRAL VARIABILITY IN HYPERSPECTRAL IMAGERY

open access: yes, 2019
Hyperspectral unmixing has attained a great importance in recent decades in remote sensing applications. Due to some external effect (illumination conditions) or internal effects (concentration of chlorophyll), spectral variability exists in ...
Bacher, Raphael   +4 more
core   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Development of a new spectral library classifier for airborne hyperspectral images on heterogeneous environments [PDF]

open access: yes, 2011
The classification of hyperspectral images on heterogeneous environments without prior knowledge about the study area is a challenging task. Finding potential pure spectral signatures or endmembers (EM) of the various surface materials within an image is
Mende, Andre   +4 more
core  

Considering spectral variability for optical material abundance estimation

open access: yes, 2017
Hyperspectral images include information enabling the determination of material abundances. Due to the fact that the acquisition of hyperspectral images is time consuming and the processing of these images is computationally costly, we propose an optical
Krippner, Wolfgang   +5 more
core   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Spectral Variability of Romano's Star

open access: yes, 2010
accepted for publication in RevMexAA; 19 pages, 6 tables, 6 ...
Maryeva, O., Abolmasov, P.
openaire   +2 more sources

A toy model for the X-ray spectral variability of active galactic nuclei

open access: yes, 2014
Investigations into the long-term X-ray spectral variability of 10 active galactic nuclei (AGNs) revealed a positive spectral index-flux correlation for each object.
Cao, Xinwu, Wang, Jun-Xian
core  

A Measure of Variability in Comovement for Economic Variables : a Time-Varying Coherence Function Approach [PDF]

open access: yes
In this paper, we test the instability of comovement, in time and frequency domain, for the GDP growth rate of the US and the UK. We use the frequency approach, which is based on evolutionary spectral analysis (Priestley, 1965-1996).
Mohamed Boutahar, Essahbi Essaadi
core   +2 more sources

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

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