Results 161 to 170 of about 153,264 (305)

Probing X-Ray Timing and Spectral Variability in the Blazar PKS 2155–304 over a Decade of XMM-Newton Observations

The Astrophysical Journal
Blazars, a class of active galactic nuclei (AGN) powered by supermassive black holes, are known for their remarkable variability across multiple timescales and wavelengths.
Gopal Bhatta, Suvas Chandra Chaudhary, Niraj Dhital, Tek P. Adhikari, Maksym Mohorian, Adithiya Dinesh, Radim Pánis, Raghav Neupane, Yogesh Singh Maharjan   +8 more
doaj   +1 more source

A Simulation Study Using Terrestrial LiDAR Point Cloud Data to Quantify Spectral Variability of a Broad-Leaved Forest Canopy. [PDF]

Sensors (Basel), 2018
Cifuentes R, Van der Zande D, Salas-Eljatib C, Farifteh J, Coppin P.   +4 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

On spectral synthesis in several variables

, 2017
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

An Informed and Systematic Method to Identify Variable Mid-L Dwarfs

The Astrophysical Journal
Most brown dwarfs show some level of photometric or spectral variability. However, finding the most variable dwarfs more suited for a thorough variability monitoring campaign remained a challenge until a few years ago with the design of spectral indices ...
Natalia Oliveros-Gomez, Elena Manjavacas, Daniella C. Bardalez Gagliuffi, Theodora Karalidi, Johanna M. Vos, Jacqueline K. Faherty   +5 more
doaj   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Statistical modelling and variability of the subtropical front, New Zealand [PDF]

, 2008
Ocean fronts are narrow zones of intense dynamic activity that play an important role in global ocean-atmosphere interactions. Of particular significance is the circumglobal frontal system of the Southern Ocean where intermediate water masses are formed,
Hopkins, Joanne, Hopkins, Joanne E.
core  

Optical Monitoring and Long-term Optical Spectral Variability of BL Lacertae Object S5 0716+714

The Astrophysical Journal Supplement Series
We present photometric observations of the BL Lacertae object S5 0716+714 with a temporal resolution of 120 s in the Sloan ${i}^{{\prime} }$ and ${r}^{{\prime} }$ bands.
Huai-Zhen Li, Di-Fu Guo, Long-Hua Qin, Fen Liu, Hong-Tao Liu, Ting-Feng Yi, Quan-Gui Gao, Shi-Feng Huang, Xing Gao, Xu Chen   +9 more
doaj   +1 more source