ATP effects on response of human erythrocyte membrane to high pressure
Biophysics and Physicobiology, 2019 Phosphorylation of membrane proteins in human erythrocytes is mediated by intracellular ATP levels. Such phosphorylation modulates the interactions of the bilayer with the cytoskeleton and affects the membrane stability under high pressure.
Takeo Yamaguchi, Shunji Fukuzaki
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Metabolic dependence of protein arrangement in human erythrocyte membranes. I. Analysis of spectrin-rich complexes in ATP-depleted red cells [PDF]
, 1978 J Palek, SC Liu, LM Snyder
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The Journal of Cell Biology, 2005 In 1971, “next to nothing was known about the organization of membrane proteins,” says S. Jonathan Singer (University of California, San Diego, CA). Singer had proposed that there were two kinds of membrane proteins— integral and peripheral—but the idea was, at the time, largely speculative (Singer, 1971).
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A regional analysis of alpha-spectrin in the isolated Mauthner neuron and in isolated axons of the goldfish and rabbit [PDF]
, 1985 Edward Koenig, Elizabeth A. Repasky
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β-Spectrin Regulates the Hippo Signaling Pathway and Modulates the Basal Actin Network*
Journal of Biological Chemistry, 2015 Background: The Hippo signaling pathway is regulated by mechanical signals from the cytoskeleton. Results: Perturbation of the spectrin cytoskeleton lead to loss of Hippo signaling phenotypes in Drosophila and mammalian cells.
K. K. Wong +6 more
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Super-Resolution Microscopy Reveals the Native Ultrastructure of the Erythrocyte Cytoskeleton
Cell Reports, 2018 Summary: The erythrocyte cytoskeleton is a textbook prototype for the submembrane cytoskeleton of metazoan cells. While early experiments suggest a triangular network of actin-based junctional complexes connected by ∼200-nm-long spectrin tetramers, later
Leiting Pan, Rui Yan, Wan Li, Ke Xu
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Haematologica, 2013 Hereditary pyropoikilocytosis is a severe hemolytic anemia caused by spectrin deficiency and defective spectrin dimer self-association, typically found in African populations.
Sabina Swierczek +8 more
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A posttranslational modification of beta-actin contributes to the slow dissociation of the spectrin-protein 4.1-actin complex of irreversibly sickled cells. [PDF]
, 1995 Archil Shartava +9 more
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Non-erythroid beta spectrin interacting proteins and their effects on spectrin tetramerization
Cellular and Molecular Biology Letters, 2011 AbstractWith yeast two-hybrid methods, we used a C-terminal fragment (residues 1697–2145) of non-erythroid beta spectrin (βII-C), including the region involved in the association with alpha spectrin to form tetramers, as the bait to screen a human brain cDNA library to identify proteins interacting with βII-C.
Sevinc, Akin, Fung, Leslie W. -M.
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, 2018 Central neurons initiate action potentials (APs) in the axon initial segment (AIS), a compartment characterized by a high concentration of voltage-dependent ion channels and specialized cytoskeletal anchoring proteins arranged in a regular nanoscale ...
Dannemeyer, Melanie +6 more
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