Results 11 to 20 of about 629,504 (222)
The PRIDE database resources in 2022: a hub for mass spectrometry-based proteomics evidences
Nucleic Acids Res., 2021 The PRoteomics IDEntifications (PRIDE) database (https://www.ebi.ac.uk/pride/) is the world's largest data repository of mass spectrometry-based proteomics data.
Yasset Pérez-Riverol +13 more
semanticscholar +1 more source
High-Resolution Native Mass Spectrometry
Chemical Reviews, 2021 Native mass spectrometry (MS) involves the analysis and characterization of macromolecules, predominantly intact proteins and protein complexes, whereby as much as possible the native structural features of the analytes are retained.
S. Tamara, M. A. den Boer, A. Heck
semanticscholar +1 more source
Liquid chromatography–tandem mass spectrometry for clinical diagnostics
Nature Reviews Methods Primers, 2022 Mass spectrometry is a powerful analytical tool used for the analysis of a wide range of substances and matrices; it is increasingly utilized for clinical applications in laboratory medicine.
Stefani N. Thomas +4 more
semanticscholar +1 more source
The Skyline ecosystem: Informatics for quantitative mass spectrometry proteomics.
Mass spectrometry reviews (Print), 2020 Skyline is a freely available, open-source Windows client application for accelerating targeted proteomics experimentation, with an emphasis on the proteomics and mass spectrometry community as users and as contributors.
Lindsay K. Pino +5 more
semanticscholar +1 more source
Advances in mass spectrometry imaging for spatial cancer metabolomics.
Mass spectrometry reviews (Print), 2022 Mass spectrometry (MS) has become a central technique in cancer research. The ability to analyze various types of biomolecules in complex biological matrices makes it well suited for understanding biochemical alterations associated with disease ...
Xin Ma, Facundo M. Fernández
semanticscholar +1 more source
Journal of the American Society for Mass Spectrometry, 2021 Biological systems are composed of heterogeneous populations of cells that intercommunicate to form a functional living tissue. Biological function varies greatly across populations of cells, as each single cell has a unique transcriptome, proteome, and ...
Michael J Taylor +2 more
semanticscholar +1 more source
A Cross-platform Toolkit for Mass Spectrometry and Proteomics
Nature Biotechnology, 2012 Mass-spectrometry-based proteomics has become an important component of biological research. Numerous proteomics methods have been developed to identify and quantify the proteins in biological and clinical samples1, identify pathways affected by ...
Matthew Chambers +42 more
semanticscholar +1 more source
Advanced Mass Calibration and Visualization for FT-ICR Mass Spectrometry Imaging [PDF]
J Am Soc Mass Spectrom. 2012 Nov;23(11):1865-72. Epub 2012 Aug 28, 2013 Mass spectrometry imaging by Fourier transform ion cyclotron resonance yields hundreds of unique peaks, many of which cannot be resolved by lower performance mass spectrometers. The high mass accuracy and high mass resolving power allow confident identification of small molecules and lipids directly from biological tissue sections.
arxiv +1 more source
The clinical spectrum of SMA‐PME and in vitro normalization of its cellular ceramide profile
Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1941-1952, December 2022., 2022 Abstract Objective The objectives of this study were to define the clinical and biochemical spectrum of spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME) and to determine if aberrant cellular ceramide accumulation could be normalized by enzyme replacement.
Michelle M. Lee +16 more
wiley +1 more source
Environmental Chemical Analysis, 2018 Download the annotations file of all identified pep-tides. Compute empirically the following P A,H2O : the probability of seeing a water loss in an ion fragment when the fragment contains acidic residues.
Somenath Mitra, P. Patnaik, B. Kebbekus
semanticscholar +1 more source