Results 41 to 50 of about 1,818,239 (291)
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Structural Evidence for the Tetrameric Assembly of Chemokine CCL11 and the Glycosaminoglycan Arixtra™. [PDF]
Understanding chemokine interactions with glycosaminoglycans (GAG) is critical as these interactions have been linked to a number of inflammatory medical conditions, such as arthritis and asthma.
Dykstra, Andrew B +2 more
core +2 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The composition of narrow distribution poly ethylene oxide-propylene oxide copolymer (Mw ~ 8700 Da) was studied using matrix assisted laser desorption ionization (MALDI) mass spectrometry.
Houshia, Orwa Jaber, Wilkins, Charles
core +1 more source
COMPUTER SIMULATION OF GAMMA-RAY DETECTOR BASED ON SCINTILLATION CRYSTALS AND SILICON PHOTOMULTIPLIERS [PDF]
Subject of Research. The paper considers the principles of realization of the gamma-radiation detector based on a silicon photoelectron multiplier and a scintillation crystal with the use of an optical matching scheme. Method.
Bokatyi I.O. +5 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Boron determination in steels by Inductively-Coupled Plasma spectometry (ICP) [PDF]
The sample is treated with 5N H2SO4 followed by concentrated HNO3 and the diluted mixture is filtered. Soluble B is determined in the filtrate by Inductively-Coupled Plasma (ICP) spectrometry after addition HCl and extraction of Fe with ethyl-ether.
Coedo, A. G., Lopez, M. T. D.
core +1 more source
Measurement of calcium isotopes (δ44Ca) using a multicollector TIMS technique [PDF]
We propose a new“multicollector technique” for the thermal ionization mass spectrometer (TIMS) measurement of calcium (Ca) isotope ratios improving average internal statistical uncertainty of the 44Ca/40Ca measurements by a factor of 2–4 and average ...
Bock, Barbara +5 more
core +1 more source
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
In this study, we focused on microfluidic electrochemical analysis of zinc complexes (Zn(phen)(his)Cl2, Zn(his)Cl2) and ZnS quantum dots (QDs) using printed electrodes.
Lukas Nejdl +12 more
doaj +1 more source

