Results 31 to 40 of about 285 (203)

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Elastic and inelastic scattering of 18O ions by 6Li at 114 MeV and isotopic differences of 6, 7Li + 18O and 6Li + 16, 18O nuclei interactions [PDF]

open access: yesЯдерна фізика та енергетика, 2012
Angular distributions of the 6Li + 18O elastic and inelastic scattering as well as the 6Li(18O, Х) reactions with production of 16,17,19O + 8,7,5Li, 14,15,16,17N + 10,9,8,7Be and 12,13,14C + 12,11,10B nuclei were measured at Elab(18O) = = 114 MeV.
A. T. Rudchik   +15 more
doaj  

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

open access: yesAdvanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar   +2 more
wiley   +1 more source

Energy dependence of the 6Li + 16O scattering and isotopic differences between potentials of the 6,7Li + 16O interactions [PDF]

open access: yesЯдерна фізика та енергетика, 2012
Experimental data of the 6Li + 16O elastic scattering at Ec.m.. = 3.27 - 36.8 MeV known from literature, were analyzed within the optical model and coupled-reaction-channels method.
A. T. Rudchik,   +7 more
doaj  

Thermomechanical Fatigue and Creep–Fatigue Interaction of Inconel 718 Additively Manufactured by Laser Beam Powder Bed Fusion

open access: yesAdvanced Engineering Materials, EarlyView.
Thermomechanical fatigue tests of laser beam powder bed fusion (PBF‐LB) Inconel 718 show that the additively manufactured material reaches almost the lifetimes of conventionally‐rolled material under no‐dwell conditions. Introducing dwell times at the maximum temperature markedly reduces the lifetimes due to pronounced grain boundary sliding associated
Stefan Guth   +6 more
wiley   +1 more source

Elastic and inelastic scattering of 12C ions by 7Li at 115 MeV [PDF]

open access: yesЯдерна фізика та енергетика, 2013
Angular distributions of the 7Li + 12C elastic and inelastic scattering as well as the 7Li(14N, Х) reactions with exited stable and unstable nuclei with Z = 3 6 were measured at Elab(12C) = 115 MeV.
A. T. Rudchik   +15 more
doaj  

The relationship between photometric and spectroscopic oscillation amplitudes from 3D stellar atmosphere simulations

open access: yesMonthly Notices of the Royal Astronomical Society, 2021
ABSTRACT We establish a quantitative relationship between photometric and spectroscopic detections of solar-like oscillations using ab initio, 3D, hydrodynamical numerical simulations of stellar atmospheres. We present a theoretical derivation as a proof of concept for our method. We perform realistic spectral line formation calculations
Yixiao Zhou   +7 more
openaire   +6 more sources

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