Results 31 to 40 of about 1,750,612 (319)
Focus image scanning microscopy for sharp and gentle super-resolved microscopy
Super-resolution microscopy techniques can be challenging for live cells and thick samples. Here, the authors propose a method to reduce beam intensity and remove out-of-focus fluorescence background in image-scanning microscopy (ISM) and its combination
Giorgio Tortarolo +9 more
doaj +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Methylammonium lead iodide perovskite, a promising material for efficient photovoltaics, shows a unique temperature dependence of its optical properties. Kim et al.
Heejae Kim +8 more
doaj +1 more source
Advanced methods for enhanced sensing in biomedical Raman spectroscopy
Raman spectroscopy is a powerful tool in the field of biomedicine for disease diagnosis owing to its potential to provide the molecular fingerprint of biological samples.
Balagopal, Bavishna
core +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Single-shot imaging of surface molecular ionization in nanosystems
Using single-shot velocity map imaging technique, explosion imaging of different ion species ejected from 50 nm SiO2 nanoparticles are obtained excitedly by strong near-infrared and ultraviolet femtosecond laser fields.
Sun Fenghao +10 more
doaj +1 more source
CASD-NMR: critical assessment of automated structure determination by NMR
NMR spectroscopy is currently the only technique for determining the solution structure of biological macromolecules. This typically requires both the assignment of resonances and a labor-intensive analysis of multidimensional nuclear Overhauser effect ...
NMR Spectroscopy +4 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
A compact two-wave dichrometer of an optical biosensor analytical system for medicine
An experimental model has been developed of a compact two-wave dichrometer on the base of LEDs that is well-suited to work with “liquid” DNA nanoconstructions as biosensing units.
Chulkov D.P. +5 more
doaj +1 more source
Application of Infrared Spectroscopy in Microalgal Research
Microalgae are rich in carotenoids, vitamins, proteins, polyunsaturated fatty acids and other nutrients required by humans and animals. In addition, some microalgae also play critical roles in aquatic ecological environment.
Liu Jing-hua +4 more
core +1 more source

