Results 51 to 60 of about 2,074,156 (315)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Selective Membrane Transport Systems studied by Solid-State NMR Spectroscopy [PDF]
Membranes border cells from their environment. Thus, they belong to the basic prerequisites for life as we know it. Within cells, membranes are used to establish compartments dedicated to specific tasks such as providing local proximity of components ...
Ader, C. +3 more
core +1 more source
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
A compact two-wave dichrometer of an optical biosensor analytical system for medicine
An experimental model has been developed of a compact two-wave dichrometer on the base of LEDs that is well-suited to work with “liquid” DNA nanoconstructions as biosensing units.
Chulkov D.P. +5 more
doaj +1 more source
Single-shot imaging of surface molecular ionization in nanosystems
Using single-shot velocity map imaging technique, explosion imaging of different ion species ejected from 50 nm SiO2 nanoparticles are obtained excitedly by strong near-infrared and ultraviolet femtosecond laser fields.
Sun Fenghao +10 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
All-optical field-free three-dimensional orientation of asymmetric-top molecules
Alignment and orientation of the molecules allows studying the photon-molecule interactions in greater detail. Here the authors demonstrate the three-dimensional orientation of SO2 molecules in using COLTRIMS and orthogonally polarized laser pulses but ...
Kang Lin +15 more
doaj +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Nanoconstructions on the base of double-stranded DNA molecules and their optical properties
Experimental results have been presented on studying optical properties of nanoconstructions formed of orientationally ordered neighbouring double-stranded DNA molecules in the structure of their liquid-crystalline phases and dispersion particles of ...
Skuridin S.G. +5 more
doaj +1 more source
Optically driven spin transfer is the fastest process to manipulate magnetism. Here, the authors show that this process emerges as the dominant mechanism in femtosecond spin dynamics enabling to the engineering of functional magnetic systems for future ...
Felix Willems +8 more
doaj +1 more source

