Results 51 to 60 of about 2,074,156 (315)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Selective Membrane Transport Systems studied by Solid-State NMR Spectroscopy [PDF]

open access: yes, 2009
Membranes border cells from their environment. Thus, they belong to the basic prerequisites for life as we know it. Within cells, membranes are used to establish compartments dedicated to specific tasks such as providing local proximity of components ...
Ader, C.   +3 more
core   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

A compact two-wave dichrometer of an optical biosensor analytical system for medicine

open access: yesEPJ Web of Conferences, 2017
An experimental model has been developed of a compact two-wave dichrometer on the base of LEDs that is well-suited to work with “liquid” DNA nanoconstructions as biosensing units.
Chulkov D.P.   +5 more
doaj   +1 more source

Single-shot imaging of surface molecular ionization in nanosystems

open access: yesNanophotonics, 2021
Using single-shot velocity map imaging technique, explosion imaging of different ion species ejected from 50 nm SiO2 nanoparticles are obtained excitedly by strong near-infrared and ultraviolet femtosecond laser fields.
Sun Fenghao   +10 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

All-optical field-free three-dimensional orientation of asymmetric-top molecules

open access: yesNature Communications, 2018
Alignment and orientation of the molecules allows studying the photon-molecule interactions in greater detail. Here the authors demonstrate the three-dimensional orientation of SO2 molecules in using COLTRIMS and orthogonally polarized laser pulses but ...
Kang Lin   +15 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Nanoconstructions on the base of double-stranded DNA molecules and their optical properties

open access: yesEPJ Web of Conferences, 2017
Experimental results have been presented on studying optical properties of nanoconstructions formed of orientationally ordered neighbouring double-stranded DNA molecules in the structure of their liquid-crystalline phases and dispersion particles of ...
Skuridin S.G.   +5 more
doaj   +1 more source

Optical inter-site spin transfer probed by energy and spin-resolved transient absorption spectroscopy

open access: yesNature Communications, 2020
Optically driven spin transfer is the fastest process to manipulate magnetism. Here, the authors show that this process emerges as the dominant mechanism in femtosecond spin dynamics enabling to the engineering of functional magnetic systems for future ...
Felix Willems   +8 more
doaj   +1 more source

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