Results 41 to 50 of about 1,750,612 (319)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

All-optical field-free three-dimensional orientation of asymmetric-top molecules

open access: yesNature Communications, 2018
Alignment and orientation of the molecules allows studying the photon-molecule interactions in greater detail. Here the authors demonstrate the three-dimensional orientation of SO2 molecules in using COLTRIMS and orthogonally polarized laser pulses but ...
Kang Lin   +15 more
doaj   +1 more source

Optical inter-site spin transfer probed by energy and spin-resolved transient absorption spectroscopy

open access: yesNature Communications, 2020
Optically driven spin transfer is the fastest process to manipulate magnetism. Here, the authors show that this process emerges as the dominant mechanism in femtosecond spin dynamics enabling to the engineering of functional magnetic systems for future ...
Felix Willems   +8 more
doaj   +1 more source

A NMR guided approach for CsrA–RNA crystallization

open access: yes, 2013
Structure determination of protein–nucleic acid complexes remains a challenging task. Here we present a simple method for generating crystals of a CsrA–nucleic acid complex, guided entirely by results from nuclear magnetic resonances spectroscopy (NMR ...
NMR Spectroscopy   +5 more
core   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Nanoconstructions on the base of double-stranded DNA molecules and their optical properties

open access: yesEPJ Web of Conferences, 2017
Experimental results have been presented on studying optical properties of nanoconstructions formed of orientationally ordered neighbouring double-stranded DNA molecules in the structure of their liquid-crystalline phases and dispersion particles of ...
Skuridin S.G.   +5 more
doaj   +1 more source

Superresolution concentration measurement realized by sub-shot-noise absorption spectroscopy

open access: yesNature Communications, 2022
Here, the authors use entangled photon pairs as the light source for absorption spectroscopy and demonstrate sub-shot-noise spectra in the entire visible wavelength region.
Korenobu Matsuzaki, Tahei Tahara
doaj   +1 more source

Transmission Near-Infrared (NIR) and Photon Time-of-Flight (PTOF) Spectroscopy in a Comparative Analysis of Pharmaceuticals. [PDF]

open access: yes, 2015
We present a comprehensive study of the application of photon time-of-flight spectroscopy (PTOFS) in the wavelength range 1050– 1350 nm as a spectroscopic technique for the evaluation of the chemical composition and structural properties of ...
Kamran, Faisal   +17 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Encoding terahertz holographic bits with a computer-generated 3D-printed phase plate

open access: yesScientific Reports
A sub-terahertz holographic image of a two-dimensional 576-bit data code is produced using a diffractive phase-plate element. The phase plate was designed using a modified Gerchberg-Saxton iterative algorithm to encode a focused image of the data code ...
E. Constable, J. Gospodaric, A. Pimenov
doaj   +1 more source

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