Results 41 to 50 of about 2,859,006 (301)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

ADVANCED OPTICAL TECHNIQUES TO EXPLORE BRAIN STRUCTURE AND FUNCTION [PDF]

open access: yesJournal of Innovative Optical Health Sciences, 2013
Understanding brain structure and function, and the complex relationships between them, is one of the grand challenges of contemporary sciences. Thanks to their flexibility, optical techniques could be the key to explore this complex network.
L. SILVESTRI   +4 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

A compact two-wave dichrometer of an optical biosensor analytical system for medicine

open access: yesEPJ Web of Conferences, 2017
An experimental model has been developed of a compact two-wave dichrometer on the base of LEDs that is well-suited to work with “liquid” DNA nanoconstructions as biosensing units.
Chulkov D.P.   +5 more
doaj   +1 more source

Optical inter-site spin transfer probed by energy and spin-resolved transient absorption spectroscopy

open access: yesNature Communications, 2020
Optically driven spin transfer is the fastest process to manipulate magnetism. Here, the authors show that this process emerges as the dominant mechanism in femtosecond spin dynamics enabling to the engineering of functional magnetic systems for future ...
Felix Willems   +8 more
doaj   +1 more source

Near-infrared spectroscopy after high-risk congenital heart surgery in the paediatric intensive care unit [PDF]

open access: yes, 2011
Objective: To establish whether the use of near-infrared spectroscopy is potentially beneficial in high-risk cardiac infants in United Kingdom paediatric intensive care units. Design: A prospective observational pilot study.
Hovarth   +5 more
core   +1 more source

QCD spectroscopy [PDF]

open access: yesNuclear Physics B - Proceedings Supplements, 1994
Plenary talk at Lattice 93, 18 pages of ...
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

All-optical field-free three-dimensional orientation of asymmetric-top molecules

open access: yesNature Communications, 2018
Alignment and orientation of the molecules allows studying the photon-molecule interactions in greater detail. Here the authors demonstrate the three-dimensional orientation of SO2 molecules in using COLTRIMS and orthogonally polarized laser pulses but ...
Kang Lin   +15 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

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