Results 71 to 80 of about 2,155,894 (257)

Quantitative analysis of aluminum impurities in zinc alloy by laser-induced breakdown spectroscopy

, 2019
Laser-induced breakdown spectroscopy has been employed for the spectroscopic study of a laser-produced Zn alloy plasma for the analysis of Al impurities in Zn alloy. The laser-produced Zn alloy plasma was generated by a pulsed Nd:YAG laser (105 mJ, 3 ns),
Kim, DE, Oh, KJ, Kim, DW, Yoo, KJ, Park, HK   +4 more
core   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

ISRN Spectroscopy

, 2012
ISRN Spectroscopy is a peer-reviewed, open access journal that publishes original research articles and review articles in all areas of spectroscopy. ISRN Spectroscopy is part of the ISRN series of peer-reviewed, open access journals that are designed to
SANTINI, Carlo
core   +1 more source

Isoniazid–Saccharin Salts: Synthesis, Structural Aspects, Thermal Properties and Spectroscopic Characterization

Molecules
This investigation focused on isoniazid (INH)—saccharin (SAC) salts. One hydrate and one anhydrous INH-SAC salt form were synthesized and characterized spectroscopically by Raman and infrared spectroscopy.
Rezvan Mohammadi, Ayberk Yilmaz, Nihal Sarier, José António Paixão, Gulce Ogruc Ildiz, Rui Fausto   +5 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Optical fiber sensing based on reflection laser spectroscopy [PDF]

, 2010
An overview on high-resolution and fast interrogation of optical-fiber sensors relying on laser reflection spectroscopy is given. Fiber Bragg-gratings (FBGs) and FBG resonators built in fibers of different types are used for strain, temperature and ...
De Natale, Paolo, Ralph P. Tatam, Chow, Jong H., Jong H. Chow, Mario Salza, Ballard, Nicholas, Gangopadhyay, Tarun, Paz-Soldan, Daniel, Tatam, Ralph, Ferarro, Pietro, Lam, Timothy T. -Y., Lam, Timothy T-Y, Gianluca Gagliardi, Barnes, Jack A., Daniel Paz-Soldan, Gangopadhyay, Tarun Kumar, Tatam, Ralph P., Chow, Jong, Pietro Ferraro, Tarun K. Gangopadhyay, Jack A. Barnes, Loock, Hans-Peter, Edmond Chehura, Paolo De Natale, Gangopadhyay, Tarun K., Salza, Mario, Ferraro, Pietro, Hans-Peter Loock, Nicholas Ballard, Barnes, Jack, Chehura, Edmon, Gagliardi, Gianluca, Timothy T.-Y. Lam, Lam, Timothy, Chehura, Edmond, Salza M, Lam, T.T., Gagliardi, G., Tatam RP, De Natale P, Barnes JA, Tatam, R.P., Chow JH, Ferraro P, Gangopadhyay, T.K., Chehura, E., Loock HP, Gagliardi G, PazSoldan D, Chow, J.H., Ferraro, P., Lam TTY, Salza, M., Ballard N, Chehura E, Gangopadhyay TK   +55 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Three-dimensional Analyses of Geological Materials on Nanoscale by Electron Tomography

, 2022
Electron tomography (ET), an electron-microscopy-based technique that provides three-dimensional (3D) structural information from a tilt series of two-dimensional (2D) projections, has promoted the in-depth investigation of biological molecules in ...
Wu, Xiao, Zhu, Jianxi, Xian, Haiyang, Li, Shan, Li, Rui, Xi, Jiaxin, Lin, Xiaoju, He, Hongping, Yang, Hongmei, Xing, Jieqi, Yang, Yiping, Jianxi Zhu   +11 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source