Results 71 to 80 of about 2,859,006 (301)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Ultrafast photoinduced C-H bond formation from two small inorganic molecules

open access: yesNature Communications
The formation of carbon-hydrogen (C-H) bonds via the reaction of small inorganic molecules is of great significance for understanding the fundamental transition from inorganic to organic matter, and thus the origin of life. Yet, the detailed mechanism of
Zhejun Jiang   +11 more
doaj   +1 more source

Computational conjugate adaptive optics microscopy for longitudinal through-skull imaging of cortical myelin

open access: yesNature Communications, 2023
The authors realize longitudinal deep-brain imaging through an intact mouse skull by constructing a high-speed reflection matrix microscope at 1.3 µm wavelength and developing a computational conjugate adaptive optics algorithm eliminating skull ...
Yongwoo Kwon   +7 more
doaj   +1 more source

Bottomonium Spectroscopy at CLEO [PDF]

open access: yes, 2010
Results of the latest CLEO contribution to bottomonium spectroscopy is presented, the confirmation of the eta_b(1S0) ground state of bottomonium in the radiative decay Upsilon(3S) -> gamma eta_b.
Seth, Kamal K.
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Compressive Fourier Transform Spectroscopy

open access: yes, 2010
We describe an approach based on compressive-sampling which allows for a considerable reduction in the acquisition time in Fourier-transform spectroscopy.
Katz, Ori   +2 more
core   +1 more source

Portable Spectroscopy [PDF]

open access: yesApplied Spectroscopy, 2018
Until very recently, handheld spectrometers were the domain of major analytical and security instrument companies, with turnkey analyzers using spectroscopic techniques from X-ray fluorescence (XRF) for elemental analysis (metals), to Raman, mid-infrared, and near-infrared (NIR) for molecular analysis (mostly organics).
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Electron-nuclear correlated multiphoton-route to Rydberg fragments of molecules

open access: yesNature Communications, 2019
Rydberg atoms can be created from photoexcitation of molecules using intense ultrafast laser pulses. Here the authors use a coincidence detection of electrons, ion and excited Rydberg atoms and their energy sharing to reveal the general mechanism of ...
Wenbin Zhang   +11 more
doaj   +1 more source

Home - About - Disclaimer - Privacy