Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
Area Law for the Entanglement Entropy of Free Fermions in Nonrandom Ergodic Field. [PDF]
Pastur L, Shamis M.
europepmc +1 more source
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Separation of Time Scales in Weakly Interacting Diffusions. [PDF]
Adams ZP, Engel M, Gvalani RS.
europepmc +1 more source
Microscopic derivation of Ginzburg-Landau theory and the BCS critical temperature shift in general external fields. [PDF]
Deuchert A, Hainzl C, Maier MO.
europepmc +1 more source
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
High-Contrast Random Composites: Homogenisation Framework and Spectral Convergence. [PDF]
Cherdantsev M +2 more
europepmc +1 more source
Weyl's Law for the Steklov Problem on Surfaces with Rough Boundary. [PDF]
Karpukhin M, Lagacé J, Polterovich I.
europepmc +1 more source
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Approximation of magnetic Schrödinger operators with δ -interactions supported on networks. [PDF]
Holzmann M.
europepmc +1 more source

