Results 111 to 120 of about 1,220,984 (295)
, 1982 Volume 4, Number 1 of Spectrum literary journalhttps://nwcommons.nwciowa.edu/spectrum/1006/thumbnail ...
Spectrum Contributors,
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Degenerate Anisotropic Differential Operators and Applications
Boundary Value Problems, 2011 The boundary value problems for degenerate anisotropic differential operator equations with variable coefficients are studied. Several conditions for the separability and Fredholmness in Banach-valued spaces are given.
O'Regan Donal +2 more
doaj
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Entanglement Spectrum Resolved by Loop Symmetries
18+32 pages, 5+8 figures. Comments welcome!
Yagi, Haruki, Gong, Zongping
openaire +2 more sources
, 1980 Volume 2, Number 1 of Spectrum literary journalhttps://nwcommons.nwciowa.edu/spectrum/1002/thumbnail ...
Spectrum Contributors,
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
On the Complex Spectrum of the Underlying Operator of a Reliability Model
AxiomsWe study the complex point spectral distribution of the underlying operator of the system consisting of a reliable machine, a storage buffer with infinite capacity and an unreliable machine.
Zhiyang Du, Geni Gupur
doaj +1 more source
Angle resolved photon spectrum and quasiparticle excitation spectrum in an exciton superfluid
, 2009 4+ \epsilon pages, 2 color figures ...
Ye, Jinwu, Shi, T., Jiang, Longhua
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source