Results 101 to 110 of about 1,220,984 (295)

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Resonance fluorescence in the resolvent-operator formalism

, 2017
The Mollow spectrum for the light scattered by a driven two-level atom is derived in the resolvent operator formalism. The derivation is based on the construction of a master equation from the resolvent operator of the atom-field system. We show that the
Harman, Z., Debierre, V., Z. Harman, V. Debierre   +3 more
core   +1 more source

The spectrum of α-resolvable λ-fold (K_4 - e)-designs

Ars Mathematica Contemporanea, 2016
A λ -fold G -design is said to be α -resolvable if its blocks can be partitioned into classes such that every class contains each vertex exactly α times. In this paper we study the α -resolvability for λ -fold ( K 4  −  e ) -designs and prove that the necessary conditions for their existence are also sufficient, without any ...
Gionfriddo, M., LO FARO, Giovanni, Milici, S., TRIPODI, Antoinette   +3 more
openaire   +2 more sources

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

2×2 operator matrix with real parameter and its spectrum [PDF]

E3S Web of Conferences
In the present paper we consider a linear bounded self-adjoint 2×2 block operator matrix Aμ (so called generalized Friedrichs model) with real parameter μ ∈ R.
Dilmurodov Elyor B., Tosheva Nargiza A., Turayeva Nabiya A., Karamatov Bolatbek T., Shokirova Durdona Sh.   +4 more
doaj   +1 more source

Use Dr. W.W. Carpenter's Calculi Resolvent, for the kidneys ...

, 2018
Trade card advertising Dr. W.W. Carpenter's Calculi Resolvent, a remedy prepared by the Calculi Resolvent Manufacturing Co., Cleveland, Ohio.

core  

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source