Results 121 to 130 of about 1,220,984 (295)

Spectrum, May 1979 [PDF]

open access: yes, 1979
Vol.
Spectrum Contributors,
core   +1 more source

Some new bounds on resolvent energy of a graph

open access: yesOpen Mathematics
Let GG be a simple graph of order nn with eigenvalues λ1≥λ2≥…≥λn.{\lambda }_{1}\ge {\lambda }_{2}\ge \ldots \ge {\lambda }_{n}. The resolvent energy of GG is a spectrum-based graph invariant defined as ER(G)=∑i=1n(n−λi)−1.{\rm{ER}}(G)={\sum }_{i=1}^{n ...
Altındağ İlkay   +1 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Spectrum, April 1984 [PDF]

open access: yes, 1984
Volume 6, Number 1 of Spectrum literary journalhttps://nwcommons.nwciowa.edu/spectrum/1010/thumbnail ...
Spectrum Contributors,
core   +1 more source

Spectrum, April 1981 [PDF]

open access: yes, 1981
Volume 3, Number 3 of Spectrum literary journalhttps://nwcommons.nwciowa.edu/spectrum/1005/thumbnail ...
Spectrum Contributors,
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Spectroscopic signatures of a Liouvillian exceptional spectral phase in a collective spin

open access: yesSciPost Physics Core
Non-Hermitian degeneracies of Lindblad generators (Liouvillian exceptional points) can induce non-exponential relaxation and higher-order poles in dynamical response functions.
Rafael A. Molina
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Exponential decay of two-body eigenfunctions: A review

open access: yesElectronic Journal of Differential Equations, 2000
We review various results on the exponential decay of the eigenfunctions of two-body Schrödinger operators. The exponential, isotropic bound results of Slaggie and Wichmann for eigenfunctions of Schrödinger operators corresponding to eigenvalues below ...
Peter Hislop
doaj  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

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