Results 91 to 100 of about 610,362 (284)
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Confirmation of the detection of B-modes in the Planck polarization maps
One of the main problems for extracting the Cosmic Microwave Background (CMB) from submm/mm observations is to correct for the Galactic components, mainly synchrotron, free - free and thermal dust emission with the required accuracy.
Ade +16 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Baryonic Symmetries in AdS4/CFT3: An Overview
Global symmetries play an important role in classifying the spectrum of a gauge theory. In the context of the AdS/CFT duality, global baryon-like symmetries are specially interesting.
Diego Rodriguez-Gomez
doaj +1 more source
The Eddy Diffusivity in Barotropic β-Plane Turbulence
Geostrophic turbulent eddies play a crucial role in the oceans, mixing properties such as heat, salt, and geochemical tracers. A useful reduced model for geostrophic turbulence is barotropic (2D) turbulence. The focus of this study is on 2D β -plane
Hailu Kong, Malte F. Jansen
doaj +1 more source
The paper shows certain ambiguity of the narrow-band boundary of random processes obtained by different authors. The use of filters of different widths in obtaining the envelope spectrum makes it difficult to compare the obtained results by estimating the depth of amplitude modulation in vibration diagnostics of defects in rotary machines.
openaire +3 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The advent of television technologies has significantly restructured the context within which community television producers operate. Digital technologies have undercut “spectrum scarcity” arguments for limiting access to distribution platforms and ...
Andrew Ó Baoill, Salvatore Scifo
doaj
Gaussian free fields at the integer quantum Hall plateau transition
In this work we put forward an effective Gaussian free field description of critical wavefunctions at the transition between plateaus of the integer quantum Hall effect.
R. Bondesan +2 more
doaj +1 more source
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source

