Results 101 to 110 of about 169,726 (308)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Multiantenna spectrum sensing exploiting spectral a priori information

open access: yes, 2011
Dynamic Spectrum Access (DSA) is receiving considerable interest as a means to improve spectral usage in licensed bands. In order to avoid interference to licensed users, spectrum sensing has emerged as an enabling technology for DSA.
Roberto Lopez-Valcarce   +5 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Singular spectrum analysis for effective feature extraction in hyperspectral imaging

open access: yes, 2014
As a very recent technique for time series analysis, Singular Spectrum Analysis (SSA) has been applied in many diverse areas, where an original 1D signal can be decomposed into a sum of components including varying trends, oscillations and noise ...
Zabalza, Jaime   +4 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Spectrum Sensing for Cognitive Radio.

open access: yes, 2023
This work focuses on the improvement of spectrum utilization by evaluating and proposing a subset of radio scene analysis algorithms for opportunistic spectrum access deployment in a cognitive radio network. The proposed algorithms aim to solve two problems: detecting vacant frequency channels and estimating the waveform, including modulation type ...
openaire   +2 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

NEW MODEL USING DSA TECHNIQUES AND COASIAN BARGAINING AGREEMENTS FOR SPECTRUM MANAGEMENT IN KOSOVO [PDF]

open access: yes, 2013
In each country spectrum is scarce and expensive and as such it should treated carefully in terms of efficiency usage. The spectrum can be reallocated, reassigned and resold through agreements between the participants.
Krasniqi, Fidel
core  

Spectral analysis of stratified sampling: a means to perform efficient multiband spectrum sensing

open access: yes, 2012
This paper introduces a multiband spectrum sensing technique that utilizes nonuniform stratified sampling. Capitalising on the ability of the sampling scheme to suppress aliasing, the proposed method accomplishes the sensing task using sampling rates ...
Tarczynski, A., Ahmad, B.I.
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

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