Results 41 to 50 of about 133,885 (266)

Place meaning, speculation, and emerging public perceptions of carbon-storing marine sediments in Dundalk Bay, Ireland

open access: yesEcology and Society
The natural capacity of marine sediments to capture, sequester, and store organic carbon has been recognized by researchers and policy makers for its potential to mitigate against climate change.
Tomas Buitendijk   +4 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Children’s Nonfiction, Biography, and Their Responsibilities to Children

open access: yesLiterature
A debate over whether children’s nonfiction should “speculate” was launched in 2011. Understood within the context of changing demands on children’s nonfiction, it reveals a contested construction of childhood and suggests that the rules of critical ...
Joe Sutliff Sanders
doaj   +1 more source

Subprime crisis and instability of global financial markets [PDF]

open access: yesPanoeconomicus, 2010
In order to prescribe adequate remedies to treat the current financial crisis one has to understand what in the first place went wrong. An age ago, older generations wrote that disease could not be cured without an accurate diagnosis.
Radonjić Ognjen, Zec Miodrag
doaj   +1 more source

Urban Policies and Large Projects in Central City Areas: The Example of Madrid (Spain)

open access: yesUrban Science, 2021
Since the late 20th century major, European cities have exhibited large projects driven by neoliberal urban planning policies whose aim is to enhance their position on the global market.
Dolores Brandis García
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Negation and Speculation in NLP: A Survey, Corpora, Methods, and Applications

open access: yesApplied Sciences, 2022
Negation and speculation are universal linguistic phenomena that affect the performance of Natural Language Processing (NLP) applications, such as those for opinion mining and information retrieval, especially in biomedical data.
Ahmed Mahany   +4 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

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