Results 51 to 60 of about 658,968 (309)
Urban Planning, 2020 In the capital city of Santo Domingo, Dominican Republic, climate change and environmental concerns are used to justify massive redevelopment projects in informal settlements located along the rivers Ozama and Isabela. Residents in such river communities
Raksha Vasudevan, Bjørn Sletto
doaj +1 more source
Trace-level speculative multithreaded architecture [PDF]
, 2002 This paper presents a novel microarchitecture to exploit trace-level speculation by means of two threads working cooperatively in a speculative and non-speculative way respectively.
González Colás, Antonio María +2 more
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FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Why the Law Hates Speculators: Regulation and Private Ordering in the Market for OTC Derivatives [PDF]
, 1999 A wide variety of statutory and common law doctrines in American law evidence hostility towards speculation. Conventional economic theory, however, generally views speculation as an efficient form of trading that shifts risk to those who can bear it most
Stout, Lynn A.
core +2 more sources
On Speculative Enactments [PDF]
Proceedings of the 2017 CHI Conference on Human Factors in Computing Systems, 2017 Speculative Enactments are a novel approach to speculative design research with participants. They invite the empirical analysis of participants acting amidst speculative but consequential circumstances. HCI as a broadly pragmatic, experience-centered, and participant-focused field is well placed to innovate methods that invite first-hand interaction ...
Chris Elsden +6 more
openaire +2 more sources
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Speculative Bubbles and their Components on the Real Estate Market–A Preliminary Analysis
Real Estate Management and Valuation, 2016 Various speculative phenomena arise on the real estate market, and the speculative bubble (SB) is one of the best known events of the type. Speculative bubbles still have many unidentified components, and are characterized by high research potential due ...
Brzezicka Justyna
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