Results 61 to 70 of about 133,885 (266)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Trash as a Means of Religious Communication: Warm Greetings to the General Heathen Public from the Toxic Temple

open access: yesOn_Culture
Plastic, cement and nuclear waste will not only outlast us as individuals, but probably also as a species. What we pejoratively call ‘trash’ is that which will stand for us the longest.
Kilian Jörg
doaj   +1 more source

Hakikat Sonrası Çağda Medyada Gerçekler: Maya Takvimi Söylentisinin Medyada Sunumu

open access: yesSelçuk İletişim, 2019
Tarihin her döneminde "gerçeküstü" olana ilgi gösterilmiştir. Bilimsel bilgi öncesinde, hurafeler zamanında bu durum makul kabul edilebilir. Bununla birlikte sanayi devrimini takip eden süreçte yerleşen bilimsel bilgi anlayışına ve bilginin tabana ...
Özgehan Özkan
doaj   +1 more source

Speculation and Counter-Speculation

open access: yesMaHKUscript: Journal of Fine Art Research, 2019
This paper explores the ways in which financial speculation and disruption have become common traits defining our artistic and political imagination. In this discussion a variety of notions emerge – namely, the move from value to price, from labor to debt, from revolution to disruption, and from avant garde to speculation.
openaire   +3 more sources

Speculations on Smell

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 1965
Experimental research into olfactive code, noting psychological and physiological analysis, suggesting specific chemically sensitive molecules ...
J Y, Lettvin, R C, Gesteland
openaire   +2 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

'On speculation' : after Dept. of Speculation [PDF]

open access: yes, 2022
This is a creative nonfiction essay creatively responding to the novel Dept of Speculation by Jenny Offill. It is a chapter from a book-in-progress which is a memoir that uses creative responses to poems, stories, novels, works of art and songs to explore how the acts of reading and writing impact on those who spend time on them.
openaire   +1 more source

Speculation, history, speculative history [PDF]

open access: yesAccounting History Review, 2016
Why, sometimes I've believed as many as six impossible things before breakfast.1Speculations, conjectures, suppositions, opinions – we encounter them all in history and everyday life.
openaire   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Speculative parallelization

open access: yesComputer, 2006
Producción ...
González Escribano, Arturo   +1 more
openaire   +1 more source

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