Results 81 to 90 of about 133,885 (266)
On Imaginative Criminology and Its Significance
Societies, 2015 In growing numbers criminologists are discovering the value of imaginative and creative approaches for enquiry. There is now a critical mass of criminological work that engages substantively and theoretically with cultural artefacts such as film, fiction,
Jon Frauley
doaj +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Design Method for Technological Art Projects: The Double Feedback Structure
Управление культуройThe article presents a methodological approach to the design and analysis of projects in the field of technological art intersecting with Art&Science, media art, digital art and net-art based on the principle of a double feedback loop between the viewer ...
Aleksandr D. Sizenov
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Macroeconomics of Speculation [PDF]
SSRN Electronic Journal, 2005 Despite his emphasis on the speculative character of investment decisions, Minsky paid little attention to asset price speculation per se, ignoring asset price bubbles and their macroeconomic effects. That is perhaps because his views were formed during the era of financial regulation, when speculation could do no harm as bubbles on a steady stream of ...
openaire +4 more sources
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Sustainability imaginaries by design
Sustainability: Science, Practice, & PolicyAs the scale and severity of our multiple environmental crises come into view, the question of digital technologies and how they can be designed sustainably becomes even more pressing.
Roy Bendor
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Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
FEBS Open Bio, EarlyView.IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo +6 more
wiley +1 more source
Money as Medium, Speculation and Scrypt
Lateral, 2014 Although they intervened on a culture of financialization in two very different ways, both Speculation and scrypt explore the intersection of money with the history of media, imperialism, colonialism, and computation. If capitalism is a kind of computer,
Stephanie Boluk
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Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source