Results 71 to 80 of about 191,407 (308)

Hakikat Sonrası Çağda Medyada Gerçekler: Maya Takvimi Söylentisinin Medyada Sunumu

open access: yesSelçuk İletişim, 2019
Tarihin her döneminde "gerçeküstü" olana ilgi gösterilmiştir. Bilimsel bilgi öncesinde, hurafeler zamanında bu durum makul kabul edilebilir. Bununla birlikte sanayi devrimini takip eden süreçte yerleşen bilimsel bilgi anlayışına ve bilginin tabana ...
Özgehan Özkan
doaj   +1 more source

Speculation and Counter-Speculation

open access: yesMaHKUscript: Journal of Fine Art Research, 2019
This paper explores the ways in which financial speculation and disruption have become common traits defining our artistic and political imagination. In this discussion a variety of notions emerge – namely, the move from value to price, from labor to debt, from revolution to disruption, and from avant garde to speculation.
openaire   +3 more sources

Speculation in Financial Markets: A Survey [PDF]

open access: yes
This survey covers the microeconomic theory of speculation in financial markets, since the development of the economics of uncertainty. It starts with a description of Walrasian exchange economies, both in general equilibrium –the Arrow-Debreu model and ...
Felipe Zurita
core  

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

open access: yesMolecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim   +7 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Food Crisis in the Transbaikal Region during the First World War (July 1914 - February 1917)

open access: yesНаучный диалог, 2019
The causes of the food crisis in the Trans-Baikal region during the years of the First World War are studied. Archival materials reveal the specifics of the food supply of the region as a consuming region, dependent on supplies from European Russia ...
O. M. Dolidovich
doaj   +1 more source

Speculations on Smell

open access: yesCold Spring Harbor Symposia on Quantitative Biology, 1965
Experimental research into olfactive code, noting psychological and physiological analysis, suggesting specific chemically sensitive molecules ...
J Y, Lettvin, R C, Gesteland
openaire   +2 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Platform Pragmatics

open access: yesA Peer-Reviewed Journal About
This article proposes platform pragmatics as a framework for understanding collective behaviour and forms of labour within platform ecosystems. It contributes to the field of platform criticism by problematising a certain view of users as passive ...
Edoardo Biscossi
doaj   +1 more source

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