Results 71 to 80 of about 309,299 (297)

Design Research and Object-Oriented Ontology

Open Philosophy, 2020
In this paper we recount several research projects conducted at ImaginationLancaster (http://imagination.lancs.ac.uk) a Design-led research laboratory, all of which consider Object-Oriented Ontology (OOO).
Lindley Joseph, Akmal Haider Ali, Coulton Paul   +2 more
doaj   +1 more source

Efficacy and Tolerability of Topotecan/Cyclophosphamide/Dinutuximab in Relapsed and Refractory High‐Risk Neuroblastoma: A Multi‐Institutional Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Chemoimmunotherapy with irinotecan, temozolomide, and dinutuximab (I/T/DIN) has emerged as first‐line therapy for relapsed/refractory (r/r) high‐risk neuroblastoma (HRNB) in North America. Topotecan and cyclophosphamide (T/C) are often used in combination with dinutuximab in the setting of lack of response, progression, or incomplete ...
Benjamin J. Lerman, Madeleine King, Rajen Mody, Sara‐Jane Onyeama, Araz Marachelian, Thomas Cash, Sara M. Federico, Meaghan Granger, Ami V. Desai, Suzanne Shusterman, Jennifer H. Foster, Elizabeth Sokol, Chelsee Greer, Keri Streby, Holly J. Meany, Kieuhoa T. Vo, Margaret E. Macy, Rochelle Bagatell   +17 more
wiley   +1 more source

Exploring value dilemmas of brain monitoring technology through speculative design scenarios

Journal of Responsible Technology
In the field of brain monitoring, the advancement of more user-friendly wearable and non-invasive devices is introducing new opportunities for application outside the lab and clinical use.
Martha Risnes, Erik Thorstensen, Peyman Mirtaheri, Arild Berg   +3 more
doaj   +1 more source

Mixed reality digital technologies in the automotive design process [PDF]

Architecture Papers of the Faculty of Architecture and Design STU, 2020
The role of automotive design is evolving very quickly. Designers are finding themselves involved in new domains which require a different skill set, different tools, and more importantly a fresh mindset. As designers we are supposed to be able to manage
Mgr. art. Ondrej Dóci, doc. Ing. Peter Olah, ArtD., Mgr. art. Miroslav Truben   +2 more
doaj  

Design Fiction Diegetic Prototyping: A Research Framework for Visualizing Service Innovations [PDF]

, 2019
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Purpose: This paper presents a design fiction diegetic prototyping methodology and research framework for ...
Belk, Russell, Garry, Tony, Harwood, Tracy   +2 more
core   +1 more source

Clinical Course and Impact of Breaks in Therapy for Children With Relapsed/Refractory Solid Tumors

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Pediatric relapsed or refractory (R/R) solid tumors carry a dismal prognosis, and postrelapse patient experiences are not well described. We present postrelapse outcomes, including number of R/R events and subsequent therapy regimens.
Matthew T. McEvoy, Elizabeth L. Seashore, W. Susan Cheng, Shondra Clay, Jessica A. Casas, Jennifer H. Foster   +5 more
wiley   +1 more source

Human connections. Design interactive artefacts through narration and speculation

Agathón, 2020
The research in design today is looking for solutions that repair the problems that design itself has created, however, focusing only on reactive attitude is no longer sufficient for the current complexity of the system.
Andrea Di Salvo, Andrea Arcoraci
doaj   +1 more source

Criterion‐Related Validity of the Neuropsychological Quick Assessment for Screening Cognitive, Motor, and Behavioral Impairments in Patients With Pediatric Brain Tumors: An Observational Pilot Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neuropsychological complications may impair the qualitative prognosis of patients with pediatric brain tumors. However, multifaceted evaluations cannot be conducted in all patients because they are time consuming and burdensome for patients.
Ami Tabata, Keita Ueda, Tsukasa Ueno, Katsutsugu Umeda, Kentaro Ueno, Kanade Tanaka, Noyuri Nishida, Rie Yamawaki, Megumi Nukui, Yoshiki Arakawa   +9 more
wiley   +1 more source

Speculative Design for Ecological Literacy: Envisioning a Food Carbon Emissions Labeling System [PDF]

, 2019
This thesis identifies one of the most significant causes of carbon emissions (CO2e) which is the production and transportation of animal products from producers to consumers.
Buck, Angeline Ruth
core  

The Efficacy and Safety of Bevacizumab/Irinotecan/Temozolomide (BIT) for Relapsed/Refractory Neuroblastoma: The UK Children's Cancer and Leukaemia Group Experience

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with high‐risk neuroblastoma who either are refractory to induction chemotherapy or relapse following multi‐modal treatment have a dismal prognosis. Based on data from the BEACON trial, since 2021 the UK national guidelines recommend bevacizumab, irinotecan, and temozolomide (BIT) for patients with relapsed/refractory ...
Thomas J. Jackson, Menna Shamma, Upeka Senanayake, Shaimaa Sahmoud, Kathleen Duffin, Victoria Howard, David King, Ayesha Fathani, Blanche Lumb, Andrei Pobischan, Irum Latif Memon, Monzir Ahmed, Rhian Thomas, Gerard Millen, Yasmeen Alomari, Sucheta Vaidya, Lynley V. Marshall, Sally L. George, Ramya Ramanujachar, Juliet Gray, Paola Angelini   +20 more
wiley   +1 more source