Results 41 to 50 of about 2,130 (284)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Speculative sons of Ulysses and the inhuman “worlds without people”
Filosofický časopis, 2023 The paper focuses on the repeated and systematic references to the figure of Ulysses in the work of Quentin Meillassoux, Ray Brassier, Eugene Thacker, and Reza Negarestani. These are not random occurrences; Ulysses represents a key figure in the mutually
Váša, Ondřej
doaj +1 more source
Kapwani Kiwanga’s Alien Speculations
Images Re-Vues, 2017 This paper examines the work of Paris-based artist Kapwani Kiwanga (b. Canada, 1978), whose work is marked by an innovative combination of techniques from visual art, performance, and social science. I focus on Kiwanga’s performance piece, The Deep Space
Gavin Steingo
doaj +1 more source
Speculative Realism and Its Allure
Das Questões, 2023 In discussing the developments of speculative realism for the past fifteen years, it becomes imperative to account for even the most wayward thoughts of its supposed thinkers. In this regard, philosophy and marketing are two disparate fields that seem to converge in the writings and views of Graham Harman.
openaire +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
, 2015 In this sixth issue of Speculations, a serial imprint created to explore post-continental philosophy and speculative realism, a wide range of contemporary philosophical issues pertaining to the contemporary philosophical scene is touched upon, from the ...
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
, 2014 Edited by James Trafford, Robin Mackay, and Luke Pendrell. Documenting a roundtable on the ramifications of Speculative Realism for aesthetics, this discussion ranges from contemporary art's relation to the aesthetic, to accelerationism and abstraction ...
Trafford, James +4 more
core
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source