Results 81 to 90 of about 2,962,455 (275)

Investigating the shortcomings of HMM synthesis [PDF]

open access: yes, 2013
This paper presents the beginnings of a framework for formal testing of the causes of the current limited quality of HMM (Hidden Markov Model) speech synthesis.
King, Simon, Merritt, Thomas
core   +1 more source

Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity

open access: yesMolecular Oncology, EarlyView.
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek   +2 more
wiley   +1 more source

Speech Perception Is Speech Learning

open access: yesCurrent Directions in Psychological Science
Speech conveys both linguistic messages and a wealth of social and identity information about a talker. This information arrives as complex variations across many acoustic dimensions. Ultimately, speech communication depends on experience within a language community to develop shared long-term knowledge of the mapping from acoustic patterns to the ...
openaire   +2 more sources

Listening while Speaking: Speech Chain by Deep Learning

open access: yes, 2017
Despite the close relationship between speech perception and production, research in automatic speech recognition (ASR) and text-to-speech synthesis (TTS) has progressed more or less independently without exerting much mutual influence on each other.
Nakamura, Satoshi   +2 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Government Speech and the War on Terror [PDF]

open access: yes, 2017
This Article examines how the government’s speech in the War on Terror can threaten free speech, equal protection, and due process values. It focuses primarily on the constitutional harms threatened by the government’s speech itself (what some call a ...
Norton, Helen
core   +3 more sources

Effects of Lombard Reflex on the Performance of Deep-Learning-Based Audio-Visual Speech Enhancement Systems

open access: yes, 2018
Humans tend to change their way of speaking when they are immersed in a noisy environment, a reflex known as Lombard effect. Current speech enhancement systems based on deep learning do not usually take into account this change in the speaking style ...
Jensen, Jesper   +3 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Entertaining Satan: Why We Tolerate Terrorist Incitement [PDF]

open access: yes, 2017
Words are dangerous. That is why governments sometimes want to suppress speech. The law of free speech reflects a settled decision that, at the time that law was adopted, the dangers were worth tolerating.
Koppelman, Andrew
core   +1 more source

Home - About - Disclaimer - Privacy