Results 81 to 90 of about 59,347 (306)

KESANTUNAN BERBAHASA DALAM TINDAK TUTUR PADA BUKU CERITA ANAK ABANGKU SAYANG KARYA MARION

open access: yesRetorika, 2017
Politeness in Speech Acts in Abangku Sayang" Story  Book Written by Marion. This study aims to describe the acts of speech and politeness in a book book of my beloved by Marion. The research used pragmatic approach with descriptive method.
Istiqamah Istiqamah
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Internet-Memes als multimodale Sprechakte in öffentlichen Diskursen anhand von Beispielen aus Antwortthreads von @realDonaldTrump

open access: yesLinguistik Online, 2020
Internet memes are highly relevant for digital communications but there is not much re-search about their pragmatic uses. Besides being texts, memes are also multimodal speech acts. They are very similar to the speech acts Searle described, but there are
Andreas Osterroth
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Requests and refusals in English and Chinese [PDF]

open access: yes, 2008
In this thesis, I study the speech acts of request and refusal in Chinese and English. The aim of this study is to not only compare the results between Chinese and English in the realization patterns in the two speech acts, but also between my ...
Li, Li
core  

SPEECH ACTS IN INDONESIA INDEPENDENCE DAY SPEECH

open access: yes, 2018
This study is concerned with the use of speech acts in Indonesia Independence  Day Speech. The objective of this study were to describe the types of speech acts of  President’s speech in 72nd Indonesia Independence Day 2017 , the most dominant types of ...
Siti Rahma Ritonga, Ritonga, Siti Rahma
core   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Indirect Speech Acts Of Utterances In TheIntervention Movie

open access: yes, 2018
This research focuses to find the type of indirect speech acts and to knowthe function of each type of indirect speech acts that writer has found on the data.It is a qualitative research that used George Yule indirect speech acts theory(1996) as the main
Alfi Syahriyani, Ilham Leo Maulana
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

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