Results 41 to 50 of about 114,305 (261)

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Speech disorder prevention

open access: yesMaestro y Sociedad, 2017
Language therapy has trafficked from a medical focus until a preventive focus. However, difficulties are evidenced in the development of this last task, because he is devoted bigger space to the correction of the disorders of the language.
Miladis Fornaris-Méndez   +1 more
doaj  

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Foreign Language Syndrome: Neurological and Psychiatric Aspects

open access: yesNeurology International
Foreign Language Syndrome (FLS) is a rare neuropsychiatric condition characterized by the sudden, involuntary use of a non-native language, with concurrent loss or suppression of the native language. Distinct from Foreign Accent Syndrome (FAS), FLS often
Ansam Eghzawi, Ali Madha, Rany Aburashed
doaj   +1 more source

The role of educational and clinical prevention of dental diseases in older preschool children in a preschool

open access: yesУчёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2013
A study of 19 preschool children (8 ofthem with speech disorders, 19 parents, 4 preschool teacher were to identify low hygienic knowledge and skills of parents and children. Children in violation of the formation of speech found in the playback lag motor
N. P. Vanchakova   +3 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

A study of the clinical efficacy of frankincense in the acute phase of ischemic stroke [PDF]

open access: yesAdvanced Herbal Medicine, 2015
Background and aims: Ischemic stroke is the most common type of stroke and its most important symptoms are paralysis and movement disorders. Therefore, finding a method for treating this disorder is greatly important.
Nahid Jivad   +4 more
doaj  

Network Localization of Fatigue in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Fatigue is among the most common symptoms and one of the main factors determining the quality of life in multiple sclerosis (MS). However, the neurobiological mechanisms underlying fatigue are not fully understood. Here we studied lesion locations and their connections in individuals with MS, aiming to identify brain networks ...
Olli Likitalo   +12 more
wiley   +1 more source

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela   +13 more
wiley   +1 more source

Carbamazepin induced speech disorder: A case report

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Carbamazepine is similar to tricyclic antidepresants as the structure. the appropriate effective dose is 800-1200 mg/day. serum level is 8-12mg/L.Common side effects of carbamazepine are sedation, headache, and diplopia, and dizziness, nausea, vomiting ...
Bahar Sarı Narğis   +3 more
doaj  

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