Results 51 to 60 of about 2,073,624 (303)

Lombard speech synthesis using transfer learning in a Tacotron text-to-speech system

, 2019
Currently, there is increasing interest to use sequence-to-sequence models in text-to-speech (TTS) synthesis with attention like that in Tacotron models.
Bajibabu Bollepalli, Paavo Alku, Bollepalli, Bajibabu, Alku, Paavo, Lauri Juvela, Juvela, Lauri   +5 more
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Carbamazepin induced speech disorder: A case report

Psychiatry and Clinical Psychopharmacology, 2021
Carbamazepine is similar to tricyclic antidepresants as the structure. the appropriate effective dose is 800-1200 mg/day. serum level is 8-12mg/L.Common side effects of carbamazepine are sedation, headache, and diplopia, and dizziness, nausea, vomiting ...
Bahar Sarı Narğis, Gökhan Akdemir, Asena Akdemir, Gökhan Çavuş   +3 more
doaj  

Case report: Compound heterozygous NUP85 variants cause autosomal recessive primary microcephaly

Frontiers in Neurology, 2023
Nucleoporin (NUP) 85 is a member of the Y-complex of nuclear pore complex (NPC) that is key for nucleocytoplasmic transport function, regulation of mitosis, transcription, and chromatin organization.
Ethiraj Ravindran, Ethiraj Ravindran, Ethiraj Ravindran, Gaetan Lesca, Gaetan Lesca, Louis Januel, Linus Goldgruber, Achim Dickmanns, Henri Margot, Angela M. Kaindl, Angela M. Kaindl, Angela M. Kaindl   +11 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Speech disorder prevention

Maestro y Sociedad, 2017
Language therapy has trafficked from a medical focus until a preventive focus. However, difficulties are evidenced in the development of this last task, because he is devoted bigger space to the correction of the disorders of the language.
Miladis Fornaris-Méndez, Félix Lázaro Huepp-Ramos   +1 more
doaj  

Foreign Language Syndrome: Neurological and Psychiatric Aspects

Neurology International
Foreign Language Syndrome (FLS) is a rare neuropsychiatric condition characterized by the sudden, involuntary use of a non-native language, with concurrent loss or suppression of the native language. Distinct from Foreign Accent Syndrome (FAS), FLS often
Ansam Eghzawi, Ali Madha, Rany Aburashed
doaj   +1 more source

THE PREVALENCE OF STUTTERING, VOICE DISORDER, AND SPEECH SOUND DISORDERS IN PRESCHOOLERS IN SHAHREKORD, IRAN

International Journal of Child, Youth & Family Studies, 2016
The inability to communicate easily and clearly can have far-reaching debilitating effects, not only in childhood, but throughout a lifetime. The aim of this study was to determine the prevalence of stuttering, voice disorder, and speech sound disorders ...
Omid Mohamadi, Mohammad Rahimi-Madiseh, Morteza Sedehi   +2 more
doaj   +1 more source