Results 81 to 90 of about 2,073,624 (303)

Digital Technology Supporting Children's Speech Therapy

Applied Medical Informatics, 2023
Considering that all children are attracted to technology and spend a lot of time using digital technology, it would be advisable to use IT support for education and/or therapy.
Mihaela CRIŞAN-VIDA, Lăcrămioara STOICU-TIVADAR, Bogdana VIRAG, Tiberiu DUGHI   +3 more
doaj  

Speech and language difficulties in children with and without a family history of dyslexia [PDF]

, 2010
Comorbidity between SLI and dyslexia is well documented. Researchers have variously argued that dyslexia is a separate disorder from SLI, or that children with dyslexia show a subset of the difficulties shown in SLI.
Carroll, Julia M., Carroll, Julia M.; id_orcid, Myers, Joanne M.   +2 more
core   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Private Speech and Inner Speech in Typical and Atypical Development [PDF]

, 2010
Children often talk themselves through their activities: They produce private speech to regulate their thought and behaviour, which is internalised to form inner speech, or silent verbal thought.
LIDSTONE, JANE,STEPHANIE,MAY, Lidstone, Jane Stephanie May   +1 more
core  

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Brainstem encoding of speech and musical stimuli in congenital amusia: evidence from Cantonese speakers [PDF]

, 2015
Congenital amusia is a neurodevelopmental disorder of musical processing that also impacts subtle aspects of speech processing. It remains debated at what stage(s) of auditory processing deficits in amusia arise.
Wong, PCM, Maggu, Akshay R., Maggu, Akshay R, Lau, Joseph CY, Akshay R. Maggu, Patrick C. M. Wong, Lau, Joseph C. Y., Wong, Patrick C. M., Fang Liu, Lau, JCY, Joseph C. Y. Lau, Wong, Patrick CM, Fang eLiu, Liu, F, Maggu, AR, Akshay Raj Maggu, Liu, Fang   +16 more
core   +1 more source

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

Theta and alpha oscillatory signatures of auditory sensory and cognitive loads during complex listening

NeuroImage
The neuronal signatures of sensory and cognitive load provide access to brain activities related to complex listening situations. Sensory and cognitive loads are typically reflected in measures like response time (RT) and event-related potentials (ERPs ...
Brilliant, Y. Yaar-Soffer, C.S. Herrmann, Y. Henkin, A. Kral   +4 more
doaj   +1 more source