Results 41 to 50 of about 498,468 (303)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Ultrax:An Animated Midsagittal Vocal Tract Display for Speech Therapy [PDF]
, 2012 Speech sound disorders (SSD) are the most common communication impairment in childhood, and can hamper social development and learning. Current speech therapy interventions rely predominantly on the auditory skills of the child, as little technology is ...
Renals, S., Richmond, K.
core +1 more source
International Archives of Otorhinolaryngology, 2013 Summary Introduction: Chronic obstructive pulmonary disease is characterized by progressive and partially reversible obstruction of pulmonary airflow.
Marina Rodrigues Bueno Macri +6 more
doaj +1 more source
Cognitive Research, 2022 Mask-wearing during the COVID-19 pandemic has prompted a growing interest in the functional impact of masks on speech and communication. Prior work has shown that masks dampen sound, impede visual communication cues, and reduce intelligibility.
Sarah E. Gutz +3 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
コミュニケーション障害の疫学 : 音声言語・聴覚障害の有病率と障害児者数の推定 [PDF]
, 2016 Communication disorders have a variety of etiologies, and the number of persons with defective speech-language and hearing is needed to provide the demand-supply models and quality education for speech and hearing specialists.
外山 稔, 松平 登志正, 苅安 誠
core
Jaw Rotation in Dysarthria Measured With a Single Electromagnetic Articulography Sensor [PDF]
, 2017 Purpose This study evaluated a novel method for characterizing jaw rotation using orientation data from a single electromagnetic articulography sensor.
Berry, Jeffrey +3 more
core +2 more sources
International Archives of Otorhinolaryngology, 2018 Introduction Computerized auditory training (CAT) has been building a good reputation in the stimulation of auditory abilities in cases of auditory processing disorder (APD). Objective To measure the effects of CAT in students with APD, with
Ândrea de Melo +3 more
doaj +1 more source
Scientific Reports, 2023 The goals of the current study were to evaluate audibility and cortical speech processing, and to provide insight into binaural processing in children with single-sided deafness (CHwSSD) using a cochlear implant (CI).
Y. Yaar-Soffer +5 more
doaj +1 more source