Results 81 to 90 of about 1,226,261 (295)

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Terapia logopedyczna przez zabawę

open access: yesLogopedia Silesiana, 2015
The purpose of the study is to present certain play which can be successfully applied to the speech therapy of children with the abnormal execution [š, ž, č, ǯ, r]. The speech therapy is conducted through fun. The form undertaken is to encourage children
Martyna Polczyk
doaj  

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

open access: yesMolecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen   +19 more
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Realization of Competent Approach in Pupils' Speech Development in Studying Metaphor

open access: yesRussian Language Studies, 2012
The article within the frame of modern competence approach to native language teaching validates the efficiency of the key competence building in the process of metaphor studying as a polyfunctional phenomenon of mentality, the language and speech ...
A B Maximova
doaj  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Developmental Speech Difficulties

open access: yes, 2015
Developmental speech difficulties is a term used to cover difficulties that some children have with their articulation, phonological and/or prosodic development.
The Specialists in Specific Speech Impairment Network
core   +3 more sources

Modern approaches to complex psycho-correctional work on preventing preschoolers’ stuttering

open access: yesНауковий Вісник Південноукраїнського Національного Педагогічного Університету імені К. Д. Ушинського, 2019
The article investigates the theoretical foundations and practical implementation of the complex approach to psycho-corrective work on overcoming stuttering.
Lytovchenko Olha
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

SPEECH THERAPY ASSISTANCE TO CHILDREN OF MIDDLE PRESCHOOL AGE BY MEANS OF COMPUTER DIDACTIC GAMES

open access: yesІнформаційні технології і засоби навчання
The article highlights the peculiarities of speech therapy assistance to children of middle preschool age using computer didactic games. All the children who were assisted had generalized underdevelopment of speech (GUS).
Viktor Hladush   +3 more
doaj   +1 more source

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