Results 101 to 110 of about 118,715 (309)

The intelligibility of Lombard speech : communicative setting matters

open access: yes, 2012
Recently we reported that talkers modified their speech production strategies in noise as a function of whether their interlocutor could or could not be seen, i.e. face-to-face (FTF) or non-visual conditions (NV).
Davis, Chris (R11605)   +2 more
core  

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Disordered speech in dementia [PDF]

open access: yes
What is the effect on language of the progressive degenerative disorder, Alzheimer's disease (AD)? What are the functional consequences of this illness, particularly for speech?
Astell, Arlene Jean
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

The effect of seeing the interlocutor on auditory and visual speech production in noise

open access: yes, 2011
Talkers modify their speech production in noisy environment partly as a reflex but also as an intentional communicative strategy to facilitate the transmission of the speech signal to the interlocutor.
Davis, Chris (R11605)   +2 more
core  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Analysis of speech production real-time MRI

open access: yes, 2018
Recent advances in real-time magnetic resonance imaging (RT-MRI) have made it possible to study the anatomy and dynamic motion of the vocal tract during speech production with great detail.
Narayanan, Shrikanth,   +21 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

The development of lexical tone production in Thai children, 18 months to 6 years : relationships with language milestones?

open access: yes, 2006
Research on tone languages is relatively scarce compared with that on non-tonal languages. Nowhere is this more apparent than in first language (L1) acquisition, especially the acquisition of lexical tone production.
Tsukada, Kimiko   +5 more
core  

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

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