Results 141 to 150 of about 6,921,546 (301)
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
A Theory That Never Was: Wrong Way to the “Dawn of Speech”
BiolinguisticsRecent literature argues that a purportedly long-standing theory—so-called “laryngeal descent theory”—in speech evolution has been refuted (Boë et al., 2019, https://doi.org/10.1126/sciadv.aaw3916).
Axel G. Ekström
doaj +1 more source
Disordered speech in dementia [PDF]
What is the effect on language of the progressive degenerative disorder, Alzheimer's disease (AD)? What are the functional consequences of this illness, particularly for speech?
Astell, Arlene Jean
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers +19 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro +14 more
wiley +1 more source
The effect of seeing the interlocutor on auditory and visual speech production in noise
, 2011 Talkers modify their speech production in noisy environment partly as a reflex but also as an intentional communicative strategy to facilitate the transmission of the speech signal to the interlocutor.
Davis, Chris (R11605) +2 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction/Objective Acute intracranial stenting during endovascular thrombectomy (EVT) for ischemic stroke requires intraprocedural antiplatelet therapy (APT) to maintain patency. However, the hemorrhagic risk of combining APT with intravenous thrombolysis (IVT) remains uncertain.
Aaron Rodriguez‐Calienes +75 more
wiley +1 more source
, 2006 Research on tone languages is relatively scarce compared with that on non-tonal languages. Nowhere is this more apparent than in first language (L1) acquisition, especially the acquisition of lexical tone production.
Tsukada, Kimiko +5 more
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Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane +10 more
wiley +1 more source