Results 121 to 130 of about 263,095 (308)

Correlatos perceptivos e acústicos dos ajustes supraglóticos na disfonia Perceptive and acoustic correlates of supraglottis adjustments in dysfonia

Revista CEFAC, 2007
OBJETIVO: avaliar os correlatos perceptivo-auditivos (ajustes supraglóticos) e acústicos (formantes) da qualidade vocal de indivíduos disfônicos com alterações glóticas, atendidos em ambulatório de fonoaudiologia de uma instituição hospitalar da cidade ...
Aline Magri, Sabrina Cukier-Blaj, Delmira de Fraga e Karman, Zuleica Antonia de Camargo   +3 more
doaj   +1 more source

Ketogenic Diet as an Epigenetic Therapy in SETD1B‐Related Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Histone lysine methyltransferases such as SETD1B regulate chromatin structure and gene transcription. Ketone bodies, including butyrate, act as histone deacetylase inhibitors. We report a 4‐year‐old boy with SETD1B‐related absence epilepsy, refractory to conventional medications, who achieved sustained > 90% seizure reduction on the Modified ...
Erica Tsang, Brian S. Gloss, Jessica P. Hayes, Andrew J. A. Holland, Manoj P. Menezes, Joceline A. Branson, Shekeeb S. Mohammad, Jingya J. Yan, Shrujna Patel, Velda X. Han, Russell C. Dale   +10 more
wiley   +1 more source

Parallel Reference Speaker Weighting for Kinematic-Independent Acoustic-to-Articulatory Inversion [PDF]

, 2016
Acoustic-to-articulatory inversion, the estimation of articulatory kinematics from an acoustic waveform, is a challenging but important problem. Accurate estimation of articulatory movements has the potential for significant impact on our understanding ...
Berry, Jeffrey J., Ji, An, Johnson, Michael T.   +2 more
core   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

On the avoidance of voiced sibilant affricates [PDF]

, 2010
In this paper it is argued that several typologically unrelated languages share the tendency to avoid voiced sibilant affricates. This tendency is explained by appealing to the phonetic properties of the sounds, and in particular to their aerodynamic ...
Zygis, Marzena
core  

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Stimulability: auxiliary measure in the identification of difficulty in speech sounds production.

Jornal da Sociedade Brasileira de Fonoaudiologia, 2012
To analyze the effectiveness of stimulability as a complementary task to the diagnosis of speech sound disorders (SSD), and to describe the performance of children with absent sounds from the phonetic inventory according to stimulable absent sounds, severity, gender, age, and occurrence of different phonological processes.Participants were 130 male and
Márcia Mathias de, Castro, Haydée Fiszbein, Wertzner   +1 more
openaire   +1 more source

Prognostic Value of Neurofilament Light Chain and Glial Fibrillary Acidic Protein in ALD‐Related Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background X‐linked adrenoleukodystrophy (X‐ALD) is a neurometabolic disorder caused by pathogenic variants in ABCD1, leading to slowly progressive spinal cord disease in nearly all affected men. Sensitive biomarkers to quantify disease severity and predict progression are needed for clinical care and trial design.
Eda G. Kabak, Marije M. C. Voermans, Hans Heijst, Charlotte E. Teunissen, Marc Engelen   +4 more
wiley   +1 more source

Tracking Articulator Movements Using Orientation Measurements [PDF]

, 2012
This paper introduces a new method to track articulator movements, specifically jaw position and angle, using 5 degree of freedom (5 DOF) orientation data. The approach uses a quaternion rotation method to accomplish this jaw tracking during speech using
Berry, Jeffrey J., Ji, An, Johnson, Michael T   +2 more
core   +1 more source