Results 231 to 240 of about 2,933,329 (294)

Pitch Strength & Percent Vocal Creak to Assess Treatment Response in Adductor Laryngeal Dystonia

open access: yesThe Laryngoscope, EarlyView.
Pitch Strength (PS) and Percent Vocal Creak (%VC) were measured before and after botulinum neurotoxin treatment in patients with adductor laryngeal dystonia (AdLD). While PS and %VC correlated with changes in disruption frequency and perceptual severity, they did not demonstrate robust group‐level treatment sensitivity.
Jesse D. Hoffmeister   +5 more
wiley   +1 more source

Multicenter Study Results on Expanded Indications in Med‐EL Pediatric Cochlear Implant Population

open access: yesThe Laryngoscope, EarlyView.
ABSTRACT Objectives To demonstrate safety and efficacy of MED‐EL cochlear implants (CIs) in children aged < 12 months and in children aged 12–71 months with residual hearing. Methods This was a multicenter, nonrandomized, single‐subject, repeated‐measures study with prospective (N = 38; 26 < 12 months of age) and retrospective (N = 209; 70 < 12 months ...
Nancy M. Young   +11 more
wiley   +1 more source

Invention of the Flexible Fiberoptic Nasopharyngolaryngoscope: Perspectives From the East

open access: yesThe Laryngoscope, EarlyView.
The fiberoptic nasopharyngolaryngoscope was developed in 1967 by Drs. Masayuki Sawashima, Hajime Hirose, and Osamu Fujimura at the University of Tokyo's Research Institute of Logopedics and Phoniatrics (RILP), building on Dr. Shigeto Ikeda's 1962 fiberoptic bronchoscope during Japan's postwar surge in technological innovation.
Carolyn J. Khoury   +7 more
wiley   +1 more source

Beyond Reality Avoidance: Unraveling the Paradox of Escapism Through Self‐Monitoring and Autonomy Mechanisms for Consumers' Life Satisfaction

open access: yesPsychology &Marketing, EarlyView.
ABSTRACT This study introduces the Paradox of Escapism, exploring how the act of escaping reality can evolve from a short‐term avoidance strategy to a mechanism for self‐regulation and enhanced life satisfaction. Employing five rigorous, multimethod investigations, including qualitative interviews and sentiment analysis (Study 1), Structural Equation ...
Thamiris Magalhães de Sousa   +3 more
wiley   +1 more source

Breathe, Eat, Talk: Three Essential Ingredients to Quality‐of‐Life Outcomes in Movement Disorders

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Breathing, eating, and talking (BET) impairments are common yet frequently underrecognized features of movement disorders. Deficits in respiration, swallowing, voice, and speech may emerge early in the course of a disease, adversely affecting safety, participation, and quality of life.
John Dean   +16 more
wiley   +1 more source

Transcranial Pulse Stimulation Enhances Dexterity in Parkinson's Disease: A Randomized Sham‐Controlled Trial

open access: yesMovement Disorders, EarlyView.
Abstract Background Ultrasound‐based neuromodulation, capable of reaching deep brain areas with high precision, represents cutting‐edge technology in non‐invasive brain stimulation and is investigated as a novel treatment for neurological and psychiatric disorders, including Parkinson's disease (PD).
Eva Matt   +14 more
wiley   +1 more source

Key Interventions in Friedreich's Ataxia and Their Impact on Patient Outcomes: A Systematic Review

open access: yesMovement Disorders, EarlyView.
Abstract Friedreich's ataxia (FA) is a rare neurodegenerative disease with multisystemic symptoms that requires multidisciplinary care. This systematic review summarizes available pharmacological and nonpharmacological interventions, their outcomes, and alignment with patient‐centered care domains, as well as their impact on these domains.
Dorota Sarwinska   +6 more
wiley   +1 more source

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

Breaking Extrapolation Barriers: Dual Innovations for Property and Component Design of Multi‐Component Alloy

open access: yesMaterials Genome Engineering Advances, EarlyView.
This study breaks extrapolation barriers in alloy design by merging symbolic regression with latent space sampling. The dual‐strategy framework enables accurate prediction of high‐hardness properties and navigates uncharted compositional spaces. The approach successfully designs novel high‐entropy alloys with hardness exceeding 863.5 HV, demonstrating ...
Zhigang Yu   +6 more
wiley   +1 more source

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