Results 61 to 70 of about 3,123,291 (286)

Functionalized Biomimetic Scaffolds for Human‐Derived Auditory Neural Circuit Construction

Advanced Science, EarlyView.
In Vitro Auditory Circuit Model. ABSTRACT Damage to auditory circuits results in sensorineural hearing loss. However, the scarcity of human inner ear tissue significantly hinders the development of therapies to preserve auditory function, creating a critical need for reliable in vitro models.
Pan Feng, Qian Zhu, Yusong Wang, Hao Rong, Xu Zhang, Fuchun Wang, Tianqi Yu, Wenxuan Wang, Jing Li, Lei Tian, Menghui Liao, Renjie Chai, Yangnan Hu   +12 more
wiley   +1 more source

The importance of deep speech phenotyping for neurodevelopmental and genetic disorders: a conceptual review

Journal of Neurodevelopmental Disorders, 2022
Background Speech is the most common modality through which language is communicated, and delayed, disordered, or absent speech production is a hallmark of many neurodevelopmental and genetic disorders.
Karen V. Chenausky, Helen Tager-Flusberg
doaj   +1 more source

Modulating Calcium Homeostasis via a Biomimetic Scaffold to Rescue Diabetic Ischemic Wounds

Advanced Science, EarlyView.
This strategy addresses impaired microcirculation and loss of extracellular matrix (ECM) guidance in diabetic wound healing. Musc@CP, a nanofibrous dressing combining an ECM‐mimetic chitosan‐pullulan scaffold with muscone, enhances perfusion by attenuating intracellular Ca2+ overload‐associated endothelial dysfunction.
Xiang Zheng, Mingmei Li, Jianjun Jiang, Yongchao Wang, Yaru Jia, Weilun Sun, Yi Yao, Pengli Gao, Linhua Zhang, Qi Guo, Guang Jia, Xing‐Jie Liang, Dunwan Zhu, Jinchao Zhang, Fangzhou Li   +14 more
wiley   +1 more source

A Window on the Genetics of Human Speech: The FOXP2 Gene [PDF]

, 2007
The development of human speech seems to be a species-specific and genetically determined capacity and is considered an extremely important step in the rise of modern humans, human culture and civilisation.
Mink, Mátyás, Solymosi, Mária Ágnes, Szűcs, Edit, Barabás, Katalin   +3 more
core   +1 more source

Automatic Speech and Voice Disorder Detection Using Deep Learning—A Systematic Literature Review

IEEE Access
Speech and voice disorders are highly prevalent and a significant concern, particularly among children. These disorders have a notable impact on individual’s personalities, academic performance and overall development.
Irum Sindhu, Mohd Shamrie Sainin
doaj   +1 more source

TECTB Variants Reveal Tectorial Membrane Vulnerability in Dominant Non‐Syndromic Hearing Loss

Advanced Science, EarlyView.
TECTB is a non‐collagenous protein of the tectorial membrane – an extracellular matrix of the cochlea. This study identifies dominant missense variants in TECTB linked to human hereditary deafness in two unrelated families. Genetically engineered mice homozygous for one of the variants are profoundly deaf, whereas heterozygous mice have normal hearing ...
Evan B. Hale, Barbara Vona, Richard J. Goodyear, Richard T. Osgood, Jun Shen, Sami S. Amr, Karen Mojica, Michaela A. H. Hofrichter, Jörg Schröder, Sophie Flandin, Paul Gratias, Ricardo Vera‐Monroy, Katherine Callahan, Kerry L. Gudlewski, Rolen Quadros, Masato Ohtsuka, JoAnn McGee, Edward J. Walsh, Cynthia C. Morton, Thomas Haaf, Channabasavaiah Gurumurthy, James E. Saunders, Guy P. Richardson, Artur A. Indzhykulian   +23 more
wiley   +1 more source

Prevalence of Speech Disorders in Arak Primary School Students, 2014-2015 [PDF]

Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2016
Background: The speech disorders may produce irreparable damage to childs speech and language development in the psychosocial view. The voice, speech sound production and fluency disorders are speech disorders, that may result from delay or impairment ...
Abdoreza Yavari, Farhad Fatehi, Hamid Dalvand, Akram Valizadeh, Rahmatollah Moradzadeh, Farideh Sadat Mirhoseini   +5 more
doaj  

ALGORITHM OF PATIENT’S TREATMENT WITH THE PRESENCE ANOMALIES OF BITE AND SPEECH DISORDERS

Український стоматологічний альманах, 2018
Relevance of research. Under complex correction of speech disorders in existing orthodontic pathology, it is important to establish the causative factor, because incorrect tongue articulation, infantile type of swallowing and other bad habits can be the
P.S. Flis, N.V. Raschenko, A.O. Melnyk, V.V. Filonenko, A.B. Lopoha   +4 more
doaj   +1 more source

Correction of Dysgraphy of Primary School Children with General Speech Underdevelopment

Развитие образования, 2022
This article is devoted to the disclosure of the content of the correctional work of a speech therapist in violation of written speech with children with general underdevelopment of speech.
Maria A. Sibarova, Klavdiya I. Sultanbaeva   +1 more
doaj   +1 more source

Pronunciation analysis for children with speech sound disorders [PDF]

2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2015
Phonological disorders affect 10% of preschool and school-age children, adversely affecting their communication, academic performance, and interaction level. Effective pronunciation training requires prolonged supervised practice and interaction. Unfortunately, many children do not have access or only limited access to a speech-language pathologist ...
Shiran Dudy, Meysam Asgari, Alexander Kain   +2 more
openaire   +2 more sources