Results 41 to 50 of about 3,404,707 (247)

Concatenative speech synthesis: a Framework for Reducing Perceived Distortion when using the TD-PSOLA Algorithm [PDF]

open access: yes
This thesis presents the design and evaluation of an approach to concatenative speech synthesis using the Titne-Domain Pitch-Synchronous OverLap-Add (I'D-PSOLA) signal processing algorithm.
Longster, Jennifer Ann
core   +8 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Speech synthesis, Speech simulation and speech science [PDF]

open access: yes, 2002
Speech synthesis research has been transformed in recent years through the exploitation of speech corpora - both for statistical modelling and as a source of signals for concatenative synthesis.
Huckvale, M
core  

Lombard speech synthesis using transfer learning in a Tacotron text-to-speech system

open access: yes, 2019
Currently, there is increasing interest to use sequence-to-sequence models in text-to-speech (TTS) synthesis with attention like that in Tacotron models.
Bajibabu Bollepalli   +5 more
core   +1 more source

Emotional Speech Synthesis Method Based on PSOLA and DCT [PDF]

open access: yesJisuanji gongcheng, 2017
Emotional speech synthesis is expected to make the synthesized speech more expressive.In order to synthesis more natural emotional speech signals,this paper proposes a new emotional speech synthesis method combining Pitch Synchronous Overlap Add(PSOLA ...
LI Yong,WEI Dang,WANG Liuyu
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Multi Speaker Natural Speech Synthesis Using Generative Flows

open access: yesСовременные информационные технологии и IT-образование, 2021
Modern speech synthesis systems generate natural speech and have high performance. Models using generative flows, among others, have shown impressive results, allowing you to form a variety of speech pronunciation from a given text.
Dmitry Obukhov
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

A real-time voice cloning system with multiple algorithms for speech quality improvement.

open access: yesPLoS ONE, 2023
With the development of computer technology, speech synthesis techniques are becoming increasingly sophisticated. Speech cloning can be performed as a subtask of speech synthesis technology by using deep learning techniques to extract acoustic ...
Weixin Hu, Xianyou Zhu
doaj   +1 more source

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