Results 51 to 60 of about 50,727 (310)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
A real-time voice cloning system with multiple algorithms for speech quality improvement.
PLoS ONE, 2023 With the development of computer technology, speech synthesis techniques are becoming increasingly sophisticated. Speech cloning can be performed as a subtask of speech synthesis technology by using deep learning techniques to extract acoustic ...
Weixin Hu, Xianyou Zhu
doaj +1 more source
Lombard speech synthesis using transfer learning in a Tacotron text-to-speech system
, 2019 Currently, there is increasing interest to use sequence-to-sequence models in text-to-speech (TTS) synthesis with attention like that in Tacotron models.
Bajibabu Bollepalli +5 more
core +1 more source
Text Preprocessing for Speech Synthesis [PDF]
, 2006 In this paper we describe our text preprocessing modules for English text-to-speech synthesis. These modules comprise rule-based text normalization subsuming sentence segmentation and normalization of non-standard words, statistical part-of-speech ...
Pfitzinger, Hartmut R. +5 more
core +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Recent development of the HMM-based speech synthesis system (HTS) [PDF]
, 2009 A statistical parametric approach to speech synthesis based on hidden Markov models (HMMs) has grown in popularity over the last few years. In this approach, spectrum, excitation, and duration of speech are simultaneously modeled by context-dependent ...
Tokuda, Keiichi +9 more
core
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Information, 2019 Text-to-speech synthesis is a computational technique for producing synthetic, human-like speech by a computer. In recent years, speech synthesis techniques have developed, and have been employed in many applications, such as automatic translation ...
Yifan Liu, Jin Zheng
doaj +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source