Results 41 to 50 of about 36,429 (223)
FEBS Open Bio, EarlyView.20 Hz mechanical vibration induced A431 cancer cells' apoptosis without such effect on other healthy cell lines of L929 and C2C12. Lowered glucose consumption is observed specifically in A431. The expressions of ROS, HMGB1, and HSP1 levels initially increase and subsequently decrease in the cancer cell line, as opposed to L929 and C2C12, which ...
Wresti L. Anggayasti +5 more
wiley +1 more source
Identifying prognostic targets in metastatic prostate cancer beyond AR
FEBS Open Bio, EarlyView.Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng +13 more
wiley +1 more source
EchoWear: Smartwatch Technology for Voice and Speech Treatments of Patients with Parkinson's Disease [PDF]
arXiv, 2016 About 90 percent of people with Parkinson's disease (PD) experience decreased functional communication due to the presence of voice and speech disorders associated with dysarthria that can be characterized by monotony of pitch (or fundamental frequency), reduced loudness, irregular rate of speech, imprecise consonants, and changes in voice quality ...
arxiv
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Purpose Four‐dimensional cone‐beam CT (4D CBCT) incorporates oversampling of 3D data to reconstruct multi‐phase CBCT data sets representing distinct phases of the breathing cycle based on a diaphragmatic correlate of respiratory motion. Motion artifacts and blurring can be reduced relative to three‐dimensional cone‐beam (3D CBCT), allowing ...
Colton Baley +4 more
wiley +1 more source
Energy dependence of the GAFCHROMIC LD‐V1 in the diagnostic radiographic modalities
Journal of Applied Clinical Medical Physics, EarlyView.Abstract The GAFCHROMIC LD‐V1 radiochromic film is widely used in dosimetry because it can provide high‐resolution two‐dimensional dose distributions without processing. This study aimed to evaluate the response characteristics at different effective energies, from the low‐energy range of mammography to the high‐energy range of computed tomography. Net
Tatsuhiro Gotanda +9 more
wiley +1 more source
Knowledge Base of an Expert System Used for Dyslalic Children Therapy [PDF]
arXiv, 2014 In order to improve children speech therapy, we develop a Fuzzy Expert System based on a speech therapy guide. This guide, write in natural language, was formalized using fuzzy logic paradigm. In this manner we obtain a knowledge base with over 150 rules and 19 linguistic variables.
arxiv
Journal of Applied Clinical Medical Physics, EarlyView.Abstract Purpose The aim of this work was to report on the optimization, commissioning, and validation of a beam model using a commercial independent dose verification software RadCalc version 7.2 (Lifeline Software Inc, Tyler, TX, USA), along with 4 years of experience employing RadCalc for offline and online monitor unit (MU) verification on the ...
Urszula Jelen +3 more
wiley +1 more source
Diagnostic Challenge in Frontal Variant Alzheimer's Disease With Low Amyloid‐β PET Retention
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Diagnosing frontal variant Alzheimer's disease (fvAD) is difficult and could be even more difficult when amyloid‐beta (Aβ) PET retention is low. A 63‐year‐old woman presenting with a 3‐year history of apathy and memory impairment showed executive dysfunction, memory impairment, and severe bilateral frontotemporal atrophy on MRI.
Ryosuke Shimasaki +5 more
wiley +1 more source
Automated Classification of Phonetic Segments in Child Speech Using Raw Ultrasound Imaging [PDF]
Proceedings of the 17th International Joint Conference on
Biomedical Engineering Systems and Technologies - Volume 1: BIOIMAGING, 2024,
pages 326-331Speech sound disorder (SSD) is defined as a persistent impairment in speech sound production leading to reduced speech intelligibility and hindered verbal communication. Early recognition and intervention of children with SSD and timely referral to speech and language therapists (SLTs) for treatment are crucial. Automated detection of speech impairment
arxiv +1 more source
HPDL Variant Type Correlates With Clinical Disease Onset and Severity
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Recently, a mitochondrial encephalopathy due to biallelic HPDL variants was described, associated with a broad range of clinical manifestations ranging from severe, infantile‐onset neurodegeneration to adolescence‐onset hereditary spastic paraplegia. HPDL converts 4‐hydroxyphenylpyruvate acid (4‐HPPA) into 4‐hydroxymandelate (4‐HMA),
Eun Hye Lee +19 more
wiley +1 more source