Results 61 to 70 of about 120,866 (259)
Unravelling social network usage patterns: A study based on unsupervised learning
Cyberpsychology: Journal of Psychosocial Research on CyberpspaceWe are facing a growing concern regarding the consequences of Problematic Social Network Use (PSNU). Therefore, the aim of the present study was to explore the profiles of social network (SN) users and contrast their differences across variables linked ...
Alfredo Zarco-Alpuente +7 more
doaj +1 more source
مجله پژوهش در علوم توانبخشی, 2011 چكيده مقدمه:اهميت فركانس سازه اي به گونه اي است كه روابط ميان سه سازه اول از اجزاي اصلي تشخيص نوع واكه توسط فرد شنونده مي باشد. به علاوه كيفيت يك واكه به بسامد سازه هاي آن بستگي دارد، بنابراين كاربرد اصلي اندازه گيري بسامد سازه در توصيف خطاهاي واكه اي ...
Faranak Salehi +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
The Persistence of language Disorders in a Group of Disadvantaged Grade 3 Learners
South African Journal of Communication Disorders, 2007 A strong correlation between early language impairment and academic failure has been suggested by past research. This follow-up cohort study of 25 monolingual, disadvantaged grade 3 learners investigated whether the language impairments diagnosed in ...
Daleen Klop, Seppo K. Tuomi
doaj +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
International Archives of Otorhinolaryngology, 2016 Introduction In Vestibular Testing (VT), caloric tests allow evaluation of unilateral weakness (UW) and directional preponderance (DP), where different criteria of normality are adopted in Brazil and worldwide.
Najlla Lopes de Oliveira Burle +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source