Results 41 to 50 of about 487,443 (254)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Contributions of speed and accuracy to translational selection in bacteria. [PDF]

PLoS ONE, 2012
Among bacteria, we have previously shown that species that are capable of rapid growth have stronger selection on codon usage than slow growing species, and possess higher numbers of rRNA and tRNA genes.
Wenqi Ran, Paul G Higgs
doaj   +1 more source

The energy–speed–accuracy trade-off in sensory adaptation [PDF]

Nature Physics, 2012
Adaptation is the essential process by which an organism becomes better suited to its environment. The benefits of adaptation are well documented, but the cost it incurs remains poorly understood. Here, by analysing a stochastic model of a minimum feedback network underlying many sensory adaptation systems, we show that adaptive processes are ...
Lan, G., Sartori, P., Neumann, S., Sourjik, V., Tu, Y.   +4 more
openaire   +4 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Analysis Of Attack Velocity and Accuracy in Banjarbaru City Fencing Athletes

Indonesian Journal of Physical Education and Sport Science
Studi purpose. The purpose of this study is to determine the Speed and Accuracy of Attacks on Fencing Athletes when making attacks lacking speed and accuracy so as to make attack techniques not optimal and effective which have an impact on points and ...
Norhalizatul Isnaniah, Herita Warni, Mita Erliana   +2 more
doaj   +1 more source

Paradoxical relationship between speed and accuracy in olfactory figure-background segregation.

PLoS Computational Biology, 2021
In natural settings, many stimuli impinge on our sensory organs simultaneously. Parsing these sensory stimuli into perceptual objects is a fundamental task faced by all sensory systems.
Lior Lebovich, Michael Yunerman, Viviana Scaiewicz, Yonatan Loewenstein, Dan Rokni   +4 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

The effect of roadside on speed perception

Acta Polytechnica CTU Proceedings
The study examines how various roadside elements, such as flat areas, trees, slopes, and buildings, influence speed perception. Data from multiple previous studies were combined and reanalyzed using newly established criteria to assess the proximity and
Martin Rak, Martin Bilík
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Conducting Web-Based Experiments for Numerical Cognition Research

Journal of Cognition, 2019
It is becoming increasingly popular and straightforward to collect data in cognitive psychology through web-based studies. In this paper, I review issues around web-based data collection for the purpose of numerical cognition research.
Arnold R. Kochari
doaj   +1 more source