Results 51 to 60 of about 487,443 (254)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The Speed–Accuracy Tradeoff as a Subject of Psychological Analysis
Вестник Кемеровского государственного университета, 2021 The present research featured the regularities, according to which the accuracy of human movements is associated with the length of these movements and time.
D. Yu. Balanev, E. V. Bredun
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Speed and accuracy of visual image discrimination by rats
Frontiers in Neural Circuits, 2013 The trade-off between speed and accuracy of sensory discrimination has most often been studying using sensory stimuli that evolve over time, such as random dot motion discrimination tasks.
Pamela eReinagel
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Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Codon-by-codon modulation of translational speed and accuracy via mRNA folding. [PDF]
PLoS Biology, 2014 Rapid cell growth demands fast protein translational elongation to alleviate ribosome shortage. However, speedy elongation undermines translational accuracy because of a mechanistic tradeoff.
Jian-Rong Yang +2 more
doaj +1 more source
Pointing with the ankle: the speed-accuracy trade-off [PDF]
Experimental Brain Research, 2013 This study investigated the trade-off between speed and accuracy in pointing movements with the ankle during goal-directed movements in dorsal-plantar (DP) and inversion-eversion (IE). Nine subjects completed a series of discrete pointing movements with the ankle between spatial targets of varying difficulty.
Michmizos, Konstantinos +1 more
openaire +4 more sources
Molecular Oncology, EarlyView.This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Redundancy-Reducing and Holiday Speed Prediction Based on Highway Traffic Speed Data
IEEE Access, 2019 The accurate prediction of the highway traffic speed plays an important role in improving the production efficiency and the convenience of lives, and it is also one of the important issues in vehicle social big data analyses.
Zhigang Gao +5 more
doaj +1 more source