Results 71 to 80 of about 473,902 (283)
Empowering precision medicine through high performance computing clusters [PDF]
, 2018 The role of High Performance Computing (HPC) in Medicine is greatly increase in these last years, moving from basic research to the clinics. With the advent of Next Generation Sequencing (NGS) technologies, diverse areas of human health have been ...
Castrignanò Tiziana +2 more
core +3 more sources
Speed–accuracy tradeoffs in animal decision making
Trends in Ecology & Evolution, 2009 The traditional emphasis when measuring performance in animal cognition has been overwhelmingly on accuracy, independent of decision time. However, more recently, it has become clear that tradeoffs exist between decision speed and accuracy in many ecologically relevant tasks, for example, prey and predator detection and identification; pollinators ...
Chittka, L., Skorupski, P., Raine, N. E.
openaire +10 more sources
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Interaction With Tilting Gestures In Ubiquitous Environments
, 2010 In this paper, we introduce a tilting interface that controls direction based applications in ubiquitous environments. A tilt interface is useful for situations that require remote and quick interactions or that are executed in public spaces. We explored
Atia, Ayman, Tanaka, Jiro
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Codon-by-codon modulation of translational speed and accuracy via mRNA folding. [PDF]
PLoS Biology, 2014 Rapid cell growth demands fast protein translational elongation to alleviate ribosome shortage. However, speedy elongation undermines translational accuracy because of a mechanistic tradeoff.
Jian-Rong Yang +2 more
doaj +1 more source
Optimizing the depth and the direction of prospective planning using information values [PDF]
, 2019 Evaluating the future consequences of actions is achievable by simulating a mental search tree into the future. Expanding deep trees, however, is computationally taxing.
Dezfouli, A. +2 more
core +3 more sources
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Speed and accuracy of visual image discrimination by rats
Frontiers in Neural Circuits, 2013 The trade-off between speed and accuracy of sensory discrimination has most often been studying using sensory stimuli that evolve over time, such as random dot motion discrimination tasks.
Pamela eReinagel
doaj +1 more source
Viable Dependency Parsing as Sequence Labeling [PDF]
, 2019 We recast dependency parsing as a sequence labeling problem, exploring several encodings of dependency trees as labels. While dependency parsing by means of sequence labeling had been attempted in existing work, results suggested that the technique was ...
Gómez-Rodríguez, Carlos +2 more
core +2 more sources