Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
A symptom network approach to schizophrenia in the CATIE study: processing speed as the central cognitive impairment. [PDF]
BJPsych OpenBuchwald K +4 more
europepmc +1 more source
Research and development of high-speed on-chip photodetectors based on AIIIBV heterostructures [PDF]
, 2019 И. В. Писаренко, E. A. Ryndin
openalex +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Effects of different training characteristics in combined resistance and cognitive training on motor and cognitive performance in older adults: A systematic review. [PDF]
Eur Rev Aging Phys ActAminirakan D, Linnhoff D, Wollesen B.
europepmc +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Design of twin delayed deep deterministic policy gradient RL based adaptive controller for DC motor speed regulation considering uncertainties. [PDF]
Sci RepGaur P +4 more
europepmc +1 more source
Announcement—International Conference on High Speed Ground Transportation to be held on the campus of Arizona State University [PDF]
, 1973 openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Speed and Distance Redistribution-Lower Limb Power Strategy in Single-Leg-Approach Jumps. [PDF]
Life (Basel)Tai WH, Peng HT, Lin JZ, Yu HB, Li PA.
europepmc +1 more source