Results 111 to 120 of about 59,744 (294)
, 2019 Numerical optimization is an important tool in the field of computational physics in general and in nano-optics in specific. It has attracted attention with the increase in complexity of structures that can be realized with nowadays nano-fabrication ...
Burger, Sven +5 more
core +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Reducing reflections from mesh refinement interfaces in numerical relativity
, 2005 Full interpretation of data from gravitational wave observations will require accurate numerical simulations of source systems, particularly binary black hole mergers.
B. Schutz +4 more
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
PERFORMANCE STUDIES OF CUSTOM CONTINUOUSLY VARIABLE TRANSMISSION FOR ALLTERRAIN VEHICLE APPLICATIONS [PDF]
Journal of Engineering Science and Technology, 2018 The off-road vehicles are a necessary in today’s world for rescuing operations, military, racing and farming applications creating a huge demand for the AllTerrain Vehicle in the automobile market. The market size is estimated to be worth about $ 9.2bn (₹
SHREYAS SASTRY V. M. +2 more
doaj
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Hız Kesiciden Elektrik Enerjisi Üretimi
Düzce Üniversitesi Bilim ve Teknoloji Dergisi, 2015 Bu çalışmada, araç hızını yavaşlatmak için kullanılan hız kesiciden yararlanarak alternatif enerji kaynağı tasarlanmıştır. Özel hız kesici tasarımı ile hidrolik sistem birleştirilmiş ve mekanik enerji üretilmiştir.
Ali DEMİRCAN +2 more
doaj +2 more sources
Numerical treatment of the Filament Based Lamellipodium Model (FBLM)
, 2015 We describe in this work the numerical treatment of the Filament Based Lamellipodium Model (FBLM). The model itself is a two-phase two-dimensional continuum model, describing the dynamics of two interacting families of locally parallel F-actin filaments.
Manhart, A. +3 more
core
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source